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ESA Corona CAD - User Manual

ESA Corona CAD
190 pages
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Corona
®
CAD
®
Detector
Corona
®Plus
CAD
®
Detector
Operating & Maintenance Manual
ESA Biosciences, Inc.
22 Alpha Road
Chelmsford, MA 01824-4171 U.S.A.
Telephone: (978) 250-7000
Fax: (978) 250-7090
www.esainc.com
P/N 70-6258 Rev. G

Table of Contents

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Summary

WARRANTY

WARNINGS AND SAFETY PRECAUTIONS

IMPORTANT OPERATING CONSIDERATIONS

CHAPTER 1: INTRODUCTION

Mode of Operation of the Detector

Explains the detection process stages: nebulization, evaporation, charging.

CHAPTER 2: INSTALLATION

Power Requirements

Details electrical connection and power specifications.

Drain and Vent Installation

Explains how to connect drain and vent tubing assembly.

CHAPTER 3: THE CORONA CAD FIRMWARE

Creating;Editing a Corona CAD Detector Method

Guides on setting up analytical methods for data acquisition.

Creating;Editing a CAD+TL Method (Timeline)

Explains how to program timed events for automated operations.

Using a Method to Collect Data

Covers selecting and running a saved method for data acquisition.

How to Create a Timeline Method

Provides an example procedure for creating a timeline method.

CHAPTER 4: USING THE DETECTOR IN AN HPLC SYSTEM

Operating the Corona Detector

Covers turning the detector on and stabilizing it.

Maximizing the Performance of the Assay

Provides tips for optimizing assay performance and detector settings.

CHAPTER 5: MAINTENANCE AND TROUBLESHOOTING

Detector Maintenance

Outlines daily, weekly, monthly, and quarterly maintenance tasks.

In-Line Filter Elements

Covers changing and checking in-line filter elements.

General Troubleshooting Approach

Offers systematic guidelines for diagnosing problems.

Internal Electronic Diagnostic Programs (Corona detector “Self Test”)

Describes the detector's built-in diagnostic test program.

Pump Noise

Identifies rhythmicity in the baseline caused by pump issues.

Mobile Phase Flow

Addresses issues with maintaining correct mobile phase flow rates.

Column

Discusses how column performance affects detector results.

Mobile Phase

Covers mobile phase issues that can cause noise or affect nebulizer.

Erratic;Noisy Baseline

Provides troubleshooting steps for baseline instability.

High Background Currents

Offers solutions for increased background current issues.

APPENDIX E: DRAIN;VENT ASSEMBLY - OLD STYLES

ESA Corona CAD Specifications

General IconGeneral
Field of View90°
Communication InterfaceWired
Coverage15 m
Detection Range15m
Current Consumption25mA (typical)
TechnologyMicrowave + Passive Infrared (PIR)