16
17
OUTLINE
Neuron anatomy and neurophysiology
EEG generation and some research ndings
Overview of non-invasive neurostimulation
IASIS basics and protocols
Some pilot data from IASIS treatment
electrical properties of Neurons
Neurons send electrical signals down their axons to communicate with
other neurons through neurotransmitter release.
They are able to do this by maintaining a negative resting potential
relative to the extracellular space.
Synapse propagation
Action potentials propagate
via voltage-gated Na+ and K+
channels that cause depo-
larization and repolarization,
respectively.
Concentration gradient is
restored by a Na+/K+ pump
which pushes 3 Na+ out and 2
K+ ions in.
Ionic concentrations in neurons
K+ is in equilibrium due to opposing forces that balance
out at resting membrane potential
Na+
Na+K+ K+
K+
Neurons are highly interconnected
Along each axon and at each synapse is a delicate balance of
electrical charge and current
Disrupting this balance will result
in altered communication between
neurons