Prologue
Warnings and Precautions
9
Handling Precautions
General Precautions
The MagNA Pure 96 Instrument is designed to ensure safe operation. However, since biological research
sample material may be processed in the instrument, there is a possible risk of infection. Therefore, when
handling potentially infectious material, always follow standard safety procedures and bear in mind the
following steps to minimize the chance of contamination or infection.
The instrument should not be used to analyze infectious materials unless additional safety measures to
ensure safe sample handling (e.g., placing the instrument in a laboratory with the appropriate safety
level, or using a purification protocol which allows external sample lysis) are taken beforehand.
Always wear a laboratory coat, gloves and a mask when handling specimens and reagents.
Immediately disinfect spills with an appropriate disinfectant solution to avoid spreading contamina-
tion to laboratory personnel or equipment.
If a specimen or other biohazardous material spills on the instrument or any of the racks, clean the
area or rack with a 10% (v/v) bleach solution (0.5% sodium hypochlorite) and then with a 70% etha-
nol solution.
Do not let water or chemicals come into contact with any electrical components.
Water or chemicals may cause damage and will void your warranty.
Unplug the equipment if it will not be used for extended periods of time.
When using the equipment, follow generally accepted procedures for quality
control and method development.
Do not attempt to disassemble the equipment. Repairs must be performed by
Roche service personnel. The equipment contains no operator-serviceable
parts.
Do not modify any part of the equipment. Modification may cause fire or mal-
function, or may void the manufacturer’s warranty.
Do not change or modify the purification protocols provided in the
MagNA Pure 96 Software. This will lead to malfunction of the MagNA Pure 96
System.
Anti-virus software is not provided. It is therefore essential to take precautions to
ensure that any software loaded onto the system is free of viruses. It is recom-
mended to install only Roche software on the control unit.
Make sure the main switch is freely accessible.
Warning of electric shock. Keep all covers closed while the instrument is con-
nected to the main power supply.
Spraying liquid on electrical parts can cause a short circuit and result in fire.
Keep the covers closed while the instrument is connected to the main power and
do not use spray in the vicinity of the MagNA Pure 96 Instrument.
Warning of explosion from sparks. Keep all potentially inflammable or explosive
material (e.g., anesthetic gas) away from the instrument.
The incubator of the process station is hot while the instrument is in operation.
Do not touch the surface of the heating block. The block is hot enough (up to
+100°C) to cause immediate burning.
Do not insert hands or fingers into either of the holes provided for discarding
waste liquids (on the right of the stage). If the reagent-dispensing nozzle head
moves suddenly, it may strike and injure your hand or fingers.
The instrument contains high-energy ultraviolet lamps which can cause serious
temporary eye and skin irritation. Never expose unprotected eyes or skin to the
UV light.
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