Maintenance and Trouble Shooting
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Maintenance and Trouble Shooting
1. User Maintenance
User Maintenance consists beside regular cleaning mostly of a regular check of the Nozzle
Head function. Other regular activities for the operator are mentioned throughout this
manual. In order to check the proper function the following routine checks are recom-
mended and explained in the course of this chapter.
Leakage Test: every 50 purification runs or every second month or if the
Nozzle Head seems to show leakage
O-ring maintenance: Greasing of O-rings: every 20 purification runs or once a week
Exchange of O-rings: If the Leakage Test indicates
It is recommended to start a ring-binder with the new instrument, where all operator
maintenance, cleaning and service engineer maintenance is documented. There should
be documented also regular checks of the system performance. If you need assistance in
creating such ring-binder, please contact your local Roche representative.
As well it is advisable to document there or in the MagNA Pure Software documentation
all operators and used reagent kit lot no.s in order to be able to perform an optimal trou-
ble shooting, if needed.
1.1 Leakage Test
Purpose
The Leakage Test will detect any leakage of air into the reaction tips, which might eventually
lead to loss of liquid. If there is a leak, the most probable cause is deteriorated or damaged
O-rings (on the Nozzle Head).
Use
We recommend that you perform a Leakage Test after two months or after 50 purifica-
tions. You should also perform a Leakage Test any time you suspect that the pipet tips are
leaking.
Note: Although wear and tear-on the O-rings is related to the number of isolations per-
formed, it is also influenced by maintenance (e.g. if the O-rings are not greased often
enough) and environmental conditions (e.g. light, chemicals). Because of this, we recom-
mend that you regularly test for leakage, even if the instrument is not used regularly.
User Maintenance
Leakage Test
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