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Scan Parameters
Data Types
14 Orbitrap Fusion Series Hardware Manual Thermo Scientific
Data Types
With the Orbitrap Fusion Series MS, you can acquire and display mass spectral data (intensity
versus mass-to-charge ratio) in one of two data types:
•Profile data
With profile data, you can see the inherent shape of the peaks in the mass spectrum. The
mass spectrum divides each atomic mass unit into several sampling intervals. The
intensity of the ion current is determined at each sampling interval. The intensity at each
sampling interval is displayed with the intensities connected by a continuous line.
• Centroid data
With centroid data, you can see the mass spectrum as a bar graph. This scan data type
sums the intensities of each set of sampling intervals. This sum is displayed versus the
integral center of mass of the many sampling intervals. Centroid data requires about
one-tenth the computer disk space of what is required for profile data.
Ion Polarity Modes
The Orbitrap Fusion Series MS can operate in either positive or negative ion polarity mode.
The mass spectrometer controls whether positive ions or negative ions are transmitted to the
mass analyzer for mass analysis by changing the polarity of the voltage potentials applied to
the API source, ion optics, and ion detection system. The ion optics are located between the
API source and the mass analyzer. For a schematic of the ion transmission path, see Figure 13.
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