Thermo Scientific Orbitrap Fusion Series Hardware Manual 61
Daily Operation
To ensure the proper operation of the Orbitrap Fusion Series system, Thermo Fisher
Scientific recommends that you perform daily preventive maintenance. This chapter specifies
the items to check before operating the system and the cleaning procedures to perform after
completing the analyses.
Clean the ion sweep cone, the spray cone, and the ion transfer tube on a regular basis to
prevent corrosion and to maintain optimum performance of the API source; see “Cleaning
the Ion Sweep Cone, Spray Cone, and Ion Transfer Tube” on page 72. If you use a mobile
phase that contains a nonvolatile buffer or inject high concentrations of sample, you might
need to clean these parts more often. It is not necessary to vent the system to flush the ion
sweep cone and ion transfer tube.
Note You do not need to calibrate the Orbitrap Fusion Series system as part of your daily
routine. Generally, you must calibrate the mass spectrometer every one to three months of
operation for optimum performance over the entire mass range of the mass detector.
For information about calibration, refer to the Orbitrap Fusion Series Getting Started
Guide.
Contents
• Before Operating the Orbitrap Fusion Series System
• After Operating the Orbitrap Fusion Series System
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