Thermo Orbitrap Fusion Series - Figure 41. Spray Cone, O-Ring, Ion Transfer Tube, and Ion Sweep Cone

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Maintenance
Maintaining the API Source Interface
76 Orbitrap Fusion Series Hardware Manual Thermo Scientific
 To clean the spray cone and O-ring
1. Soak the lint-free tissues or chamois-tipped swabs in a 50:50 solution of methanol/water,
and then clean the exterior surface of the spray cone.
2. (Orbitrap Fusion MS) Remove and inspect the O-ring located in the spray cone under
the entrance end of the ion transfer tube (Figure 41).
Figure 41. Spray cone, O-ring, ion transfer tube, and ion sweep cone (Orbitrap Fusion MS)
3. (Orbitrap Fusion MS) Clean the O-ring with methanol or replace it if necessary.
4. Using a magnification device, inspect the components for any residual lint or particulates.
5. (Orbitrap Fusion MS) Reinstall the O-ring in the spray cone.
 To clean the ion transfer tube
1. If there is extreme contamination, follow these steps. If not, start with step 2.
a. Overnight, sonicate the component in a 10% solution of Liquinox in water.
b. Rinse the component with water, and then for 2 minutes force a strong stream of
water through the orifice.
c. For 30 minutes, sonicate the component in water.
Note The Orbitrap Fusion Lumos MS does not have an O-ring behind its ion
transfer tube.
Note Inspect the inside surfaces and edges to confirm that no lint or particulates are
present. Use plastic tweezers or a similar tool to remove the lint or particulate.
IMPORTANT Always use LC/MS-grade methanol and LC/MS-grade water.
Spray cone
Ion transfer tube
API cone seal
Gas inlet on the ion
sweep cone
Vespel™ O-ring