xvii
Relationship of ionized Calcium to total Calcium
The ratio of ionized calcium to total calcium in a healthy population is around 0.50 or 50%
1,5
. These
relationships may be altered when using citrate in blood, or when the acid-base metabolism is dis-
turbed.
Specific Performance Characteristics
Reproducibility
Typical Within-Run (Swr) Between-Day (Sdd) and Total (ST) Precision is determined from 2 runs per
day with 2 replicates per run for 20 days on two AVL 9180 analyzers in each of its three configura-
tions. Values for sodium and potassium are average of all six instruments, while values for chloride,
ionized calcium and lithium are determined from the measurement of two of each respective unit
configuration. All values are reported in mmol/L.
Material: ISE-trol Protein Based Aqueous Control Material - Level 1
Parameter mean Swr (CV%) Sdd (CV%) ST (CV%)
Sodium 114.6 0.48 0.42% 0.76 0.66% 0.89 0.78%
Potassium 2.82 0.025 0.87% 0.035 1.24% 0.041 1.44%
Chloride 76.7 0.29 0.38% 0.52 0.67% 0.72 0.94%
ionized Calcium 2.07 0.015 0.72% 0.024 1.18% 0.034 1.66%
Lithium 0.40 0.010 2.40% 0.018 4.57% 0.026 6.41%
Material: ISE-trol Protein Based Aqueous Control Material - Level 2
Parameter mean Swr (CV%) Sdd (CV%) ST (CV%)
Sodium 141.2 0.40 0.28% 0.30 0.21% 0.46 0.33%
Potassium 4.35 0.024 0.55% 0.023 0.53% 0.036 0.82%
Chloride 102.4 0.18 0.18% 0.20 0.20% 0.32 0.31%
ionized Calcium 1.35 0.016 1.21% 0.021 1.55% 0.042 3.10%
Lithium 1.04 0.012 1.19% 0.035 3.36% 0.045 4.31%
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