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Christ Alpha 1-4 LSCplus User Manual

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131 pages
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Translation of the original operating manual
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Freeze-dryer
Rev. 2.3 of 03/07/2017
Alpha 1-4 LSCplus;Freeze-dryer;Alpha 2-4 LSCplus
Version 01/2011
Alpha 1-4 LSCplus
Part no. 102141
Alpha 2-4 LSCplus
Part no. 102142
Freeze-dryer
Operating Manual
Please retain for later use!

Table of Contents

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Christ Alpha 1-4 LSCplus Specifications

General IconGeneral
BrandChrist
ModelAlpha 1-4 LSCplus
CategoryDryer
LanguageEnglish

Summary

1 General Information

1.1 Importance of the Operating Manual

Explains the importance of the manual for safe operation and hazard awareness.

1.2 Intended Use

Describes the intended applications and limitations of the freeze-dryer.

1.3 Warranty and Liability

Outlines warranty and liability conditions and exclusions.

1.4 Copyright

States the copyright owner and usage restrictions for the manual.

1.5 Explanation of Symbols

Explains how specialist terms are marked in the manual (italics and arrow).

1.6 Standards and Regulations

Refers to EC Machinery Directive declaration of conformity.

1.7 Scope of Supply

Lists items included in the scope of supply and accessories.

2 Layout and Mode of Operation

2.1 Layout of the Freeze-Dryer

Describes the physical components and their arrangement on the freeze-dryer.

2.1.1 Functional and Operating Elements

Identifies and describes the main functional and operating parts of the freeze-dryer.

2.1.2 Name Plate

Details the information presented on the freeze-dryer's name plate.

2.2 Mode of Operation

Provides an overview of freeze-drying, its applications, and the basic principle of sublimation.

2.2.1 General Information on Freeze-Drying

Explains the general principles and applications of freeze-drying technology.

2.2.2 Freeze-Drying Process

Details the distinct phases of the freeze-drying process: preparation, freezing, main drying, and final drying.

3 Safety

3.1 Marking of the Unit

Illustrates and explains the various symbols and markings used on the freeze-dryer.

3.2 Explanation of the Symbols and Notes

Defines the meaning of hazard symbols (DANGER, WARNING, CAUTION, NOTE) used in the manual.

3.3 Responsibility of the Operator

Outlines the obligations and responsibilities of the freeze-dryer operator.

3.4 Operating Personnel

Specifies the requirements and qualifications for personnel operating the freeze-dryer.

3.5 Informal Safety Instructions

Provides general guidance on keeping the operating manual accessible and following safety rules.

3.6 Safety Instructions

Lists essential safety instructions to be observed before every drying process.

3.6.1 Electrical Safety

Details safety precautions related to the electrical components and power supply.

3.6.2 Mechanical Safety

Lists safety precautions for the safe mechanical operation and handling of the freeze-dryer.

3.6.3 Fire Prevention

Provides instructions to prevent fire hazards, including fuse usage and substance restrictions.

3.6.4 Thermal Safety

Highlights thermal hazards and precautions, particularly regarding the ice condenser temperature.

3.6.5 Chemical and Biological Safety

Addresses safety measures when handling hazardous chemical or biological substances.

3.7 Safety Devices

Explains the function of system checks and earth conductor checks for safety.

3.8 Procedures in the Event of Hazards and Accidents

Outlines procedures to follow in case of electrical incidents, fire, electric shock, or burns.

3.9 Remaining Hazards

Warns about potential residual hazards that cannot be completely excluded.

4 Storage and Transport

4.1 Dimensions and Weight

Provides the physical dimensions and weight specifications for the freeze-dryer models.

4.2 Storage Conditions

Specifies the required conditions for proper storage to protect the unit.

4.3 Notes on Transport

Offers guidance and warnings for safely transporting the freeze-dryer.

4.4 Packaging

Describes how the freeze-dryer is packaged and how to handle the packaging.

4.5 Transport Safety Device

Mentions the installation/deinstallation of the vacuum sensor as a transport safety measure.

5 Set-up and Connection

5.1 Installation Site

Details requirements for selecting a suitable installation location for optimal performance and safety.

5.2 Power Supply

Covers connection requirements, voltage, and safety class for the power supply.

5.3 Aeration Valve

Describes the location and function of the aeration valve.

5.4 Media Drain Valve

Details the location and use of the media drain valve for condensate removal.

5.5 Vacuum Sensor

Instructs on the installation of the vacuum sensor and refers to its separate manual.

5.6 Vacuum Pump

Guides on connecting the vacuum pump and refers to its manual, including oil mist separation.

5.7 Pressure Control Valve

Explains the function and installation of the pressure control valve.

5.8 Rubber Valves

Describes the connection and usage of rubber valves for various vessel types.

6 Operation

6.1 Initial Start-up

Provides essential checks to perform before the initial start-up of the freeze-dryer.

6.2 Installation of Accessories

Guides on the correct installation of accessories based on the drying method.

6.3 Preparation

Lists the preparation steps to be taken before switching the unit on.

6.4 Switching the Freeze-Dryer On

Explains how to turn on the freeze-dryer and the self-test procedure.

6.5 LSCplus Control System

Introduces the LSCplus control system and its user interface.

6.5.1 User Interface

Explains how to operate the system using the touch panel and its buttons.

6.5.1.1 Main Window "Manual"

Describes the main "Manual" window, its data display, and control buttons.

6.5.1.2 Main Window "Program"

Introduces the "Program" window for creating and executing drying programs.

6.5.1.3 Main Window "Options"

Explains the "Options" window for system settings and personalization.

6.5.2 Manual Freeze-Drying

Explains how to control the freeze-drying process manually phase by phase.

6.5.3 Option: Freeze-Drying with the PGMplus Programmer Module

Introduces the PGMplus module for automated, reproducible freeze-drying processes.

6.6 Optional Extensions

Lists and describes optional features and their functionalities for the freeze-dryer.

6.7 Switching the Freeze-Dryer OFF

Explains the procedure to safely switch off the freeze-dryer.

7 Malfunctions and Error Correction

7.1 General Malfunctions

Lists common malfunctions and their possible causes and corrections.

7.1.1 Power Failure

Describes how the control system handles power failures and their impact on the process.

7.1.2 Insufficient Vacuum

Addresses issues related to insufficient vacuum and checks to perform.

7.1.3 Insufficient Ice Condenser Temperature

Explains causes and effects of insufficient ice condenser temperature.

7.2 Process and Error Messages

Refers to the control system display for process and error messages.

7.3 Service Contact

Provides contact information for service inquiries, malfunctions, and spare parts.

8 Maintenance and Service

8.1 Maintenance

General guidelines and points for regular maintenance checks.

8.1.1 General

Lists general inspection points for the freeze-dryer's condition.

8.1.2 Ice Condenser Chamber

Instructions for cleaning and ensuring the ice condenser chamber is free from water residues.

8.1.3 Aeration Valve, Media Drain Valve

Details cleaning procedures for aeration and media drain valves to prevent vacuum issues.

8.1.4 Heat Exchanger

Advises on checking and cleaning the air-cooled heat exchanger to maintain performance.

8.1.5 Vacuum Pump

Provides maintenance recommendations for the vacuum pump, including oil changes.

8.1.6 Exhaust Filter

Refers to the vacuum pump and exhaust filter manuals for maintenance.

8.1.7 Vacuum Sensor

Notes the vacuum sensor's limited service life and maintenance-free nature.

8.1.8 Accessories

Highlights special safety measures for care of accessories.

8.2 Disinfection of the Drying Chamber and Accessories

Outlines procedures for disinfecting the drying chamber and accessories, especially after handling dangerous materials.

8.3 Service

Details when and how to contact service personnel for maintenance and repairs.

8.4 Return of Defective Parts

Explains the procedure for returning defective units or accessories for processing.

9 Disposal

9.1 Disposal of the Freeze-Dryer

Instructs to comply with local rules and regulations for disposal.

9.2 Disposal of the Packaging

Provides guidance on disposing of the packaging materials according to local rules.

10 Technical Data

Performance Data

Provides detailed performance specifications for ice condenser, shelf temperatures, and surface areas.

Connection Requirements

Details electrical, IP, power, and fuse requirements for connecting the unit.

Equipment Connections

Specifies connections for vacuum, media drain, aeration, vacuum sensor, and data interface.

Special Equipment: Water Cooling System

Lists technical specifications for the optional water cooling system.

10.1 Ambient Conditions

Specifies the recommended ambient temperature and humidity for operation.

10.2 Technical Documentation

Informs about availability of technical documentation and safety data sheets from the service department.

11 Appendix

11.1 Mathematical Relations

Explains mathematical calculations used in automatic processes and set value adjustments.

11.2 Brief Operating Instructions

Provides a quick overview of functional and operating elements and step-by-step instructions.

Step-by-step Instructions – Shelf Drying

Provides a detailed step-by-step guide for performing shelf drying procedures.

Step-by-step Instructions – Drying in a Flask

Offers a step-by-step guide for freeze-drying samples in flasks.

11.3 EC Declaration of Conformity

Presents the EC Declaration of Conformity for the freeze-dryer regarding the Machinery Directive.

11.4 Declaration of Conformity – China RoHS 2

Shows the Declaration of Conformity related to China RoHS 2 regulations for hazardous substances.

11.5 Resistance to Stress Cracking and Chemical Influences "Plexiglas"

Summarizes chemical resistance and stress cracking properties of Plexiglas materials.

12 Glossary

Glossary of Terms

Provides definitions for key terms used in the freeze-drying manual.

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