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The HistoCore PEGASUS is an automated tissue processor designed for in vitro diagnostic applications in histology laboratories. Its primary function is the fixation, dehydration, intermedium infiltration, and paraffin infiltration of human tissue specimens for histological medical diagnosis, such as cancer diagnosis. The device features a dual-retort system, allowing for fast and high-quality tissue processing with independent operation of both retorts, each capable of holding up to 200 cassettes in two baskets. This dual-retort design enables high-degree scheduling flexibility.
Key technical specifications include a nominal supply voltage of 100-120VAC/220-240VAC and nominal supply frequencies of 50/60Hz. Power consumption can reach a maximum of 15A for 100-120VAC and 10A for 220-240VAC, with mains input fuses rated at 16A 250VAC. The overall size of the device in operating mode is 804 x 715 x 1533 mm (Width x Depth x Height). It has an empty weight of 235kg and an overall weight of 315kg (with accessories). The operating temperature range is +10°C to +35°C, with a relative humidity of 20% to 80% non-condensing. The device requires a minimum distance of 80 mm to walls for proper functioning.
The HistoCore PEGASUS is equipped with 17 reagent bottles and 1 condensate bottle, each with a maximum volume of 3.88 L. There are also 4 paraffin baths, each with a capacity of up to 3.9 L. Paraffin melting time is approximately 7 hours at an ambient temperature of 23°C to 25°C when using "Recommended" paraffin types, and about 4.5 hours with HistoCore PEGASUS Parablocks. The paraffin melting point can be set from 50°C to 65°C, and the standby temperature from 50°C +2°C to a maximum of 71°C. Retort temperatures for paraffin can be selected from 58°C to 77°C, and for processing reagents from ambient or 35°C to 65°C. Cleaning reagents can be heated from 35°C to 85°C. The filling vacuum is -60 kPa, and draining pressure is 45 kPa. The drip tray has a capacity of >3.88L.
Usage features are enhanced by a clear, intuitive touch-screen interface that simplifies loading runs, monitoring protocols, and configuring system settings. The software allows for protocol configuration, reagent setup, and other system adjustments. An optional HistoCore I-Scan scanner (Order No.: 14 0488 58056) can be integrated to capture and record critical data, including basket ID, user ID, and reagent information, and to photograph cassettes for sample traceability. The scanner supports 1D/2D barcode scanning and image capture. The instrument also features three USB 2.0 ports for exporting logs, incident reports, and protocol files. An alarm system with two alarm sockets (for local and remote alarms) is included, along with smart error handling for specimen protection.
The system offers 20 freely configurable protocols, with 4 pre-defined protocols. Xylene pre-defined protocols consist of up to 10 reagents and 3 paraffin processing steps, while xylene-free protocols use up to 8 reagents and 3 paraffin processing steps. Protocol step times can range from 0 to 5999 minutes, and delay times up to 1000 hours. Up to 400 cassettes can be processed simultaneously. A pre-defined cleaning protocol for the retort is also available.
Maintenance features include an active carbon filter to absorb reagent fumes, which should be replaced periodically, with supervisors able to set a replacement threshold. The instrument also has a magnetic stirrer in each retort to ensure consistent temperature and good tissue penetration, which is easily removable for cleaning. Each retort has a sieve at the bottom that should be regularly checked and cleaned. The reagent cabinet is back-lit for easy level checking, and reagent bottles have an anti-spillage design. Remote fill/drain functions for reagents and paraffin minimize exposure to hazardous substances.
The software includes a Reagent Management System (RMS) that monitors reagent consumption, alerts users when reagents need replacement, and tracks reagent concentrations, cassette usage, processing runs, and days in use. This ensures consistent processing quality. The system also features overpressure, overcurrent, overheating, and over-vacuum protection mechanisms to ensure safe operation and protect specimens in case of malfunction. Regular cleaning of lids, seals, retorts, liquid level sensors, and paraffin baths is recommended, along with weekly emptying of the condensate bottle and checking bottle connectors and exterior surfaces.
General| Brand | Leica BIOSYSTEMS |
|---|---|
| Model | HistoCore PEGASUS |
| Category | Computer Hardware |
| Language | English |
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