Chapter 1: Introduction
5040237 B 9
The HumSilencer system is designed to adapt quickly to changes in noise. In a country with a
60Hz electrical grid, the response time is about 5/6th of a second to adapt to changes in the
line noise. In a country with a 50Hz electrical grid, the response time is about 1 second.
However large fast transients are problematic as a result of this ability to adapt quickly to
changes in noise. Any fast transient in the signal at the same time that the line-noise is learned
contaminates the noise average at 1/50 amplitude. This transient situation is not an issue if the
peak-to-peak broadband noise associated with the signal is greater than about 1/25 of the
amplitude of a step or spike in the signal. If the transient step or spike is larger, it is displayed
as an inverted miniature event in the noise-cancelled signal every 16.7ms or 20ms. To avoid
this situation, deselect the Adapt check box at least one second before recording fast
biological signals that have a signal-to-noise ratio greater than about 25.
For more detailed usage procedures, and to understand how controls for Episodic stimulation
mode and Gap-free data acquisition mode differ, refer to the
pCLAMP Data Acquisition and
Analysis Software v11.2 User Guide
.
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