2
Content
Safety Considerations ........................................................................................................... 3
Regulatory Statement ............................................................................................................ 5
Technical Specifications ........................................................................................................ 6
Connections ....................................................................................................................... 7
Preface .............................................................................................................................. 8
Notices............................................................................................................................... 8
Limited Warranty ................................................................................................................ 9
1. Prometheus Series Instruments ....................................................................................10
1.1. Excitation and Detection for Fluorescence Measurements .....................................10
1.2. Application Range ..................................................................................................11
1.3. Sensitivity ...............................................................................................................11
1.4. Temperature Range ...............................................................................................11
1.5. Precision ................................................................................................................11
1.6. Sample Consumption .............................................................................................11
1.7. Capillary Format .....................................................................................................12
1.8. Dedicated Control and Analysis Software ...............................................................12
2. nanoDSF Technology ....................................................................................................13
3. Using the Prometheus Series Instruments.....................................................................14
3.1. General Usage .......................................................................................................14
3.2. Sample Loading .....................................................................................................14
3.2.1. Sample Loading for the Prometheus NT.48 ........................................................15
3.2.2. Manual Sample Loading for the Prometheus NT.Plex .........................................15
3.2.3. Automated Sample Loading for the Prometheus NT.Plex ...................................16