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ThermoFisher Scientific Vanquish VC-D50 User Manual

ThermoFisher Scientific Vanquish VC-D50
188 pages
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thermo
scientific
Vanquish
Fluorescence
Detectors
VC-D50, VC-D51,
VF-D50, VF-D51
Operating Manual
4820.7901-EN Revision 2.0
December 2019

Table of Contents

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ThermoFisher Scientific Vanquish VC-D50 Specifications

General IconGeneral
BrandThermoFisher Scientific
ModelVanquish VC-D50
CategorySecurity Sensors
LanguageEnglish

Summary

1 Using this Manual

1.1 About this Manual

Describes the manual's scope, features, and operating principle.

1.2 Conventions

Explains conventions used for safety messages, notices, and typographical elements.

1.3 Reference Documentation

Lists additional hardware and software documentation for reference.

2 Safety

2.1 Safety Symbols and Signal Words

Defines safety symbols, signal words, and guidelines for observing manual safety notices.

2.2 Intended Use

Specifies the intended use of the device and laboratory practices.

2.3 Safety Precautions

Details general safety information, personnel qualifications, and protective measures.

2.4 Solvent and Additive Information

Provides guidelines on solvent compatibility, pH ranges, and concentrations.

3 Device Overview

3.1 Detector Features

Lists the main features of the fluorescence detector, including light source and detection capabilities.

3.2 Operating Principle

Explains the optical detection principle of fluorescence detectors.

3.3 Interior Components

Identifies user-accessible components located behind the device's front doors.

3.4 Flow Cell

Describes the flow cell design, its label, and identification chip.

4 Unpacking

4.1 Unpacking

Provides instructions for unpacking the device, including handling safety.

4.2 Scope of Delivery

Lists the items included in the device delivery package.

5 Installation

5.1 Safety Guidelines for Installation

Outlines critical safety guidelines to follow during device installation.

5.2 Installing the Device

Details the steps for setting up and installing the device in the Vanquish system.

5.3 Site Requirements

Specifies essential requirements for the installation site, including power.

5.5 Setting Up the Hardware

Describes how to set up the hardware and connect devices and cables.

5.6 Setting Up the Flow Connections

Provides rules and recommendations for setting up flow connections.

5.7 Determining the Pressure inside the Flow Cell

Provides procedures to determine pressure within the flow cell and its components.

5.8 Turning On the Device

Provides steps for turning on the device and its power control.

5.9 Setting Up the Device in the Software

Guides on setting up the device within the chromatography software.

6 Operation

6.2 Safety Guidelines for Operation

Highlights safety guidelines to be observed during device operation.

6.3 Control Elements

Describes the device's control elements: keypad and status indicators.

6.5 Preparing the Device for Operation

Covers steps required to prepare the device for operation and sample analysis.

6.6 Guidelines for Use of Flow Cells

Provides guidelines for handling, operating, and storing flow cells.

6.7 Operational Modes of the Detector

Lists and describes the five operational modes of the detector.

6.8 Important Operating Parameters

Lists and describes key parameters for routine operation.

6.9 Optimizing the Performance of the Device

Provides information and hints to optimize detector performance.

6.10 Shutting Down the Device

Provides instructions for shutting down the device for temporary or long-term periods.

7 Maintenance and Service

7.2 Safety Guidelines for Maintenance and Service

Lists safety guidelines crucial for performing maintenance and service.

7.3 General Rules for Maintenance and Service

Provides general rules and recommendations for successful maintenance procedures.

7.4 Routine and Preventive Maintenance

Details routine and preventive maintenance tasks for optimal performance.

7.5 Performing a Wavelength Calibration

Guides on performing wavelength calibration using water (Raman measurement).

7.7 Flow Cell

Covers cleaning and replacement of flow cells, with handling guidelines.

7.8 Replacing the Main Power Fuses

Provides instructions for replacing the main power fuses, emphasizing safety.

7.9 Updating the Device Firmware

Explains how to update the device firmware using the Chromeleon software.

7.11 Transporting or Shipping the Device

Covers preparation, transport, and shipping procedures for the device.

7.12 Replacing the Slide-In Module

Details procedures for removing, returning, and installing slide-in modules.

8 Troubleshooting

8.1 General Information about Troubleshooting

Introduces features and information to help identify and resolve problems.

8.2 Messages

Lists observed messages and provides troubleshooting assistance for each.

8.3 Operating Issues

Provides an overview of possible operating issues and their remedial actions.

9 Specifications

9.1 Performance Specifications

Details the performance specifications of the detector, including optical design and wavelength ranges.

9.2 Physical Specifications

Lists the physical specifications of the device, including dimensions and weight.

10 Accessories, Consumables and Replacement Parts

10.1 General Information

Provides general information on authorized parts and their compatibility.

10.2 Ship Kit

Lists the items included in the standard ship kit for the device.

10.3 Optional Accessories

Describes optional accessories available for flow cells and other functionalities.

10.4 Consumables and Replacement Parts

Lists consumables and replacement parts, including capillaries, cables, and fuses.

11 Appendix

11.1 Compliance Information

Details declarations of conformity, CE, cTUVus, and RoHS compliance.

11.2 UV Cutoff Wavelengths of Solvents

Explains UV cutoff wavelengths and their effect on mobile phase composition.

11.3 Digital I/O

Describes the digital I/O ports for exchanging signals with external devices.

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