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Leica BIOSYSTEMS HistoCore PEARL User Manual

Leica BIOSYSTEMS HistoCore PEARL
102 pages
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HistoCore PEARL
Tissue Processor
Instructions for Use
English
Order No.: 14 0493 80101 - Revision D
Always keep this manual with the instrument.
Read carefully before working with the instrument.
Version 1.3, Revision D - 08.2018

Table of Contents

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Leica BIOSYSTEMS HistoCore PEARL Specifications

General IconGeneral
BrandLeica BIOSYSTEMS
ModelHistoCore PEARL
CategoryLaboratory Equipment
LanguageEnglish

Summary

1. Important Information

1.1 Symbols and Meanings

Explains the meaning of various symbols used throughout the manual for warnings, notes, and instructions.

1.2 Instrument Type

Specifies the instrument type to which the manual's information applies, including serial number location.

1.3 Intended Use

Details the HistoCore PEARL's design for tissue processing from fixation to infiltration and its laboratory applications.

1.4 Personnel Qualification

Outlines the requirements for trained laboratory personnel to operate the instrument safely and effectively.

2. Safety

2.1 Safety Notes

Provides essential information related to the operating safety and maintenance of the instrument.

2.2 General Safety Warnings

Consolidates warnings regarding instrument markings, transport, installation, operation, and reagent handling.

2.3 Safety Features

Describes the built-in safety functions designed to ensure safe operation and specimen integrity.

3. Instrument Components and Specifications

3.1 Overview and Features

Provides an overview of instrument components and highlights its main features and capabilities.

3.3 Technical Data

Presents detailed technical specifications including electrical, environmental, and dimensional data.

3.4 Compatible Reagents

Lists the specific reagents that are permitted for use with the HistoCore PEARL to prevent instrument damage.

3.5 Recommended Reagent Handling

Offers guidance on recommended temperatures and procedures for handling various reagents.

4. Initial Operation

4.1 Installation and Setup

Guides users through installing, unpacking, and setting up the instrument, including site requirements and packing lists.

4.4 Instrument Hardware Components

Details the installation and function of basic instrument hardware components like the display, retort, filters, and baths.

4.5 Alarm Functions

Explains the different types of alarms (instrument, local, remote) and their functions.

4.6 Power Connection

Provides instructions and safety precautions for connecting the instrument to the power supply.

4.7 Instrument Power On

Guides the user through the procedure for powering on the HistoCore PEARL instrument.

4.8 Touchscreen Operation

Details the operation of the touchscreen interface, including status bar and main window elements.

4.9 Instrument Power Off

Outlines the correct procedure for safely switching off and shutting down the instrument.

4.10 Moving the Instrument

Provides instructions and safety precautions for moving the instrument to a new location.

5. Operation

5.1 Access Levels

Explains the different user access levels (Standard, Supervisor, Service) and their permissions.

5.2 System Setup and Configuration

Covers all system setup procedures, including language, regional settings, alarms, data, network, and maintenance.

5.3 Reagent Management

Manages reagent status, groups, stations, and the Reagent Management System (RMS).

5.4 Program Management

Covers creating, editing, deleting, and managing favorite programs for tissue processing.

5.5 Dashboard and Status

Displays instrument status including retort, paraffin baths, reagent bottles, and pipe connections.

5.6 Reagent Handling Procedures

Details safe procedures for filling, draining, and refilling reagents and paraffin.

5.7 Starting a Program

Outlines the necessary conditions and steps to initiate a processing program on the instrument.

5.8 Ending a Program

Describes the sequence of messages and actions upon completion of a processing program.

5.9 Pre-installed Programs

Details the default Overnight and Biopsy programs and their suitability for different tissue sizes.

6. Cleaning and maintenance

6.1 Cleaning Program

Explains the pre-installed cleaning program, its steps, and when it runs automatically.

6.2 General Instrument Cleaning

Covers daily, weekly, and monthly cleaning procedures for the instrument's exterior and internal parts.

6.3 Regular Maintenance Checklist

Provides a summary checklist for performing regular maintenance tasks on the instrument.

7. Troubleshooting

7.1 Troubleshooting Steps

Outlines general steps for diagnosing and resolving problems with the HistoCore PEARL.

7.2 Power Failures

Addresses issues related to power failures, including checks and sample protection measures.

7.3 Program Sequence Malfunctions

Addresses issues during program execution, including safe reagent states and software errors.

7.4 Replacing Fuses

Details the procedure for safely replacing the instrument's fuses.

8. Ordering information

9. Warranty and Service

9.1 Warranty

Describes the quality guarantee and warranty terms provided by Leica Biosystems.

9.2 Service Information

Provides contact information and required details for requesting technical support or spare parts.

9.3 Decommissioning and Disposal

Outlines the procedures for safely decommissioning and disposing of the instrument.

10. Decontamination Confirmation

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