COLUMN UNITS DESCRIPTION
Process Time hr:min Elapsed process time from beginning of concentration or diafiltration process.
Either record actual clock time or elapsed time.
Feed Temperature °C Measured temperature of process solution
Pressure Readings
Feed psi/bar Feed Pressure (PF)
Retentate psi/bar Retentate Pressure (PR)
Filtrate psi/bar Filtrate Pressure (PP)
Transmembrane Pressure (TMP) psi/bar [(PF + PR) ÷ 2] - PP
Delta P psi/bar Pressure differential (PF – PR)
Flow Rate / Flux Rate
Retentate Flow Rate L/min Measured retentate flow rate
Cross Flow Flux (CFF) L/min/ft
2
Retentate flow Rate ÷ membrane area (Liters / minute / ft
2
)
Filtrate Flow Rate mL/min Measured filtrate flow rate
Filtrate Flux Rate LMH Filtrate flow rate ÷ membrane area (Liters / hour / meter
2
)
Volume
Feed mL Remaining Feed Volume = (Starting Volume) – (Total collected filtrate volume)
(Starting Volume equals process volume added to reservoir plus hold-up
volume if system was filled with liquid.)
Filtrate mL Total collected filtrate volume
Concentration Factor X Starting Volume ÷ (Starting Volume – Filtrate Volume)
Diafiltration Volumes DV The number of DV’s of diafiltration solution added.
1 DV = Remaining Feed Volume at start of diafiltration.
Comments Indicate any observations or information considered important to fully
describe process or events.
To convert milliliters /minute to liters/ hour, multiply by 0.06
To convert square feet to square meters, multiply by 0.093
TFF Process Data Sheet Column Description
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