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Waters ACQUITY UPLC I-Class Series User Manual

Waters ACQUITY UPLC I-Class Series
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ACQUITY UPLC I-Class Series
System Guide
715005704
Revision A
Copyright © Waters Corporation 2018
All rights reserved

Table of Contents

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Waters ACQUITY UPLC I-Class Series Specifications

General IconGeneral
Data Acquisition RateUp to 100 Hz
TypeUltra Performance Liquid Chromatography (UPLC)
Maximum Operating Pressure15, 000 psi
Pressure Range0 to 15, 000 psi
Flow Rate Range0.001 to 2.0 mL/min
Flow Rate Precision<0.075% RSD
Column Temperature Range4 °C to 90 °C
Sample CapacityUp to 96 samples
pH Range1 to 12
Injection Volume0.1 to 10 μL
Detection Wavelength Range190 to 400 nm

Summary

Document Information and Legal Notices

Copyright and Trademark Notices

Legal statements regarding document use and a list of trademarks.

System Safety Considerations

System Height and Hazard Symbol Guidance

Advisories on safe module stacking and understanding hazard symbols.

Specific Electrical and Physical Hazards

Warnings related to power cords, physical hazards, and high voltage.

Bottle Placement, FCC, and Power Safety

Precautions for bottle placement, FCC emissions, and electrical power safety.

Operational Guidelines and Advisories

Equipment Misuse and General Safety Advisories

Advice on proper equipment operation and general safety warnings.

System Purpose, Audience, and Calibration Procedures

Defines system purpose, target audience, and outlines calibration/QC methods.

ACQUITY UPLC I-Class Series System Overview

UPLC Technology and System Features

Explains UPLC technology and key advantages of the I-Class Series system.

Core System Components

Details essential modules like solvent manager, injectors, and column compartments.

Advanced Options, Technology, and Detection

Covers optional modules, column technology, and detection principles.

Optimizing ACQUITY UPLC Performance

General Guidelines and System Dispersion Factors

Provides guidelines for optimal performance and explains system dispersion effects.

Carryover, Reproducibility, and Leak Prevention

Addresses carryover, reproducibility, contamination, and preventing leaks.

Fitting Installation and Assembly Recommendations

Offers guidance on installing and assembling various types of system fittings.

System Preparation and Initialization

Powering On and Initializing the System

Steps to power on the system, including workstation, modules, and software.

Module Status Indicators and LED Descriptions

Explains the meaning of various LEDs on system modules for status indication.

System Priming and Leak Sensor Configuration

Procedures for system priming and enabling leak sensors.

System Control and Console Navigation

Opening and Navigating the System Console

Guides on accessing and using the system console from different software.

Control Panel Operations for Key Modules

Details control panels for BSM, Sample Manager, Detector, and Column Manager.

System External Connections and Cabling

Ethernet, Column Heater, and General Cabling

Details Ethernet, column heater, and general external cable connections.

System Cabling and Rear Panel Layout

Illustrates the rear panel connections for various system modules.

System Plumbing and Waste Management

Shows plumbing layout, waste tubing routing, and module connections.

Electrical and Signal Connections

Details connecting to the electricity source and safety precautions.

Connecting Column Modules

Details connecting column modules (CH-A, CH-30A, CHC, CM-A, CM-Aux) via interconnect cables.

Comprehensive Safety Advisories

General Warning Symbols and System Hazards

Explains common warning symbols and general safety risks.

Specific Hazard Categories and Precautions

Covers warnings for machinery, radiation, biohazards, chemicals, and electrical safety.

Tubing, Equipment Use, and Stacking Safety

Safety advice for pressurized tubing, manufacturer specifications, and module stacking.

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