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General guidelines for the UNGUATOR
®
Mixing System
2 General Guidelines for the UNGUATOR
®
Mixing
System
2.1 Preparing the UNGUATOR
®
Mixing System
The UNGUATOR
®
Mixing System consists of an UNGUATOR
®
Jar, an UNGUATOR
®
MB
and the formulation constituents to be mixed.
First the UNGUATOR
®
Jar Cap (small white screw cap) of the UNGUATOR
®
Jar and
then the UNGUATOR
®
Jar Lid (large red or white screw cap) must be unscrewed from
the UNGUATOR
®
Jar.
Second the UNGUATOR
®
MB is inserted into the UNGUATOR
®
Jar housing, sliding
the UNGUATOR
®
Jar Bottom down. The UNGUATOR
®
Jar Lid is then slid onto the
UNGUATOR
®
MB standing in the UNGUATOR
®
Jar housing and pressed down firmly
using both thumbs. Ensure that the sealing lip of the UNGUATOR
®
Jar Lid opening is
not damaged by the bayonet noses because the ointment may otherwise rise on the
UNGUATOR
®
MB shaft during the mixing process.
Third the UNGUATOR
®
MB is removed from the UNGUATOR
®
Jar housing by pulling
with a slight counterclockwise turn. The UNGUATOR
®
Jar Lid will be moved in Mixing
Blade direction. Both parts, i.e. the UNGUATOR
®
MB and UNGUATOR
®
Jar lid are put
down or possibly tared on the balance together with the UNGUATOR
®
Jar housing.
2.2 Weighing in the Formulation Constituents
Generally, oily, greasy, aqueous and pulverized constituents can be weighed in into
the UNGUATOR
®
Jar at the same time. It is however advantageous to heed certain
general procedures to optimize the mixing results. Generally, know-how gained from
the traditional preparation of ointments is very helpful when using the UNGUATOR
®
Mixing System.
As already mentioned at the beginning of the operating instructions, the motto for use
is:
Learning by doing
Listed below are the seven different general procedures used to produce the routine
standard formulations in pharmaceutical preparation of ointments: EMULSION, EMUL-
SION +, NORMAL, SUSPENSION < 2% AND SUSPENSION > 2% as well as GEL
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