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Measurement Principle | Dynamic Light Scattering (DLS), Electrophoretic Light Scattering (ELS), Static Light Scattering (SLS) |
---|---|
Detector | Avalanche Photodiode (APD) |
Software | Zetasizer Software |
Measurement Type | Particle Size, Zeta Potential, Molecular Weight |
Particle Size Range | 0.3 nm to 10 μm |
Molecular Weight Range | 980 Da to 20 MDa |
Temperature Range | 0°C to 90°C |
Light Source | 633 nm He-Ne laser |
Minimum Sample Volume | 12 μL |
Sample Volume Range | 12 μL to 1 mL |
Explains the manual's structure, purpose, and how to navigate its sections.
Details authorized personnel and their access levels to the Zetasizer instrument.
Provides guidance on obtaining assistance from the manual and the support help desk.
Explains the core measurement capabilities: particle size, zeta potential, and molecular weight.
Details the different models within the Zetasizer Nano particle analyser series.
Provides basic explanations of the key measurement parameters.
Gives an overview of the measurement process, system components, and software functions.
Identifies the key hardware modules of the Zetasizer instrument and their functions.
Describes the key features and navigation of the main Zetasizer Nano software application.
Provides a brief overview of the measurement process using an SOP.
Details the steps for powering up the Zetasizer instrument and starting the software.
Emphasizes the importance of sample preparation for accurate measurements.
Discusses the selection of appropriate cells based on measurement type and sample.
Provides guidance on the correct procedure for filling various types of cells.
Details the process of performing a measurement using a Standard Operating Procedure (SOP).
Explains how to perform a measurement by manually setting parameters.
Describes the features and functions of the measurement display window.
Explains how to re-analyze measurement records with different parameters.
Explains how to review final measurement results displayed as records or reports.
Describes how measurement records are listed and displayed in the measurement file window.
Explains how to select and view measurement information through report tabs.
Details instrument settings like temperature, count rate, cell type, and attenuation index.
Explains the interpretation of measurement results, including Z-average size and Polydispersity Index.
Emphasizes the importance of proper sample preparation for reliable measurements.
Outlines considerations for sample preparation concerning particle size and concentration.
Details specific considerations for preparing samples for molecular weight analysis.
Outlines concentration requirements and dilution procedures for zeta potential measurements.
States that maintenance is minimal and outlines user-performed procedures.
Provides instructions for cleaning the external surfaces of the instrument safely.
Details procedures for cleaning Universal 'Dip' cells and cuvettes.
Explains how to replace system fuses and their specifications.
Explains the Zetasizer's security system for limiting user access and controlling functions.
Guides on setting up the administrator account for system configuration.
Details the process of enabling the security system within the software.
Explains how to manage user groups and their associated permissions.
Explains the benefits and methods of using SOPs for consistent measurements.
Details the steps and dialogues involved in creating a new SOP.
Describes common dialogues used across all SOP types for measurement setup.
Details specific measurement dialogues unique to size measurements within SOPs.
Details specific measurement dialogues unique to molecular weight measurements within SOPs.
Details specific measurement dialogues unique to zeta potential measurements within SOPs.
Explains how to set up SOPs for trend and protein melting point measurements.
Describes how to view and save an SOP from an existing measurement record.
Explains how to edit and save existing SOPs.
Introduces the Measurement File window for viewing and analyzing results and reports.
Describes how to open and navigate the measurement file window containing records and reports.
Explains how to customize window views by creating and selecting workspaces.
Covers methods for moving, copying, deleting, sorting, and printing measurement records.
Explains the capabilities of the Zetasizer software for exporting data to external applications.
Guides on how to export measurement files, records, or selections using various methods.
Describes how to create and modify templates for defining data export parameters.
Introduces Malvern's default reports and the use of Report Designer for custom reports.
Details how to open existing reports or create new ones using Report Designer.
Explains how to customize properties of text, parameters, pictures, frames, and calculations in reports.
Explains how to associate and view newly created custom reports within the Zetasizer software.
Outlines the chapter's aim to describe size principles and Dynamic Light Scattering.
Explains DLS as a technique for measuring particle size via Brownian motion and scattered light.
Details the physical operation of size measurements using the Zetasizer Nano system.
Outlines the chapter's aim to describe molecular weight principles and Static Light Scattering.
Explains SLS as a non-invasive technique for characterizing molecules in solution.
Explains the Debye plot and its use in determining molecular weight and the 2nd Virial Coefficient.
Outlines the chapter's aim to describe zeta potential principles and measurement operation.
Defines zeta potential and the electrical double layer around particles.
Details the M3-PALS technique for analyzing low mobility samples.
Details the physical operation of zeta potential measurements.
Covers general hazards, proper system usage, and environmental conditions.
Highlights warnings related to mains power, high voltage components, and electrical safety.
Details laser safety classifications and precautions, noting Class 1 product status.
Provides guidance on safe handling of samples and dispersants according to regulations.
Lists the technical specifications of the Zetasizer Nano system and its components.
Outlines the necessary site requirements for installing the Zetasizer Nano system.
Specifies the required environmental conditions for operating the instrument and accessories.
Details the recommended space allocation for system components and access.
Lists the power requirements for the Zetasizer Nano, Autotitrator, and computer.
Outlines the minimum PC specifications required for running the Zetasizer software.
Provides step-by-step instructions for safely unpacking the Zetasizer Nano instrument.
Explains how to re-install the Zetasizer Nano system after moving or changing computers.
Details the simple steps for connecting the Zetasizer Nano instrument to a computer.
Outlines the actions required when replacing the computer used with the instrument, including software setup.
States the product's conformance to European Commission Directives.
Provides FCC compliance information and operating conditions for the device.
Lists Canadian regulatory compliance information for digital apparatus.