How to troubleshoot high NWP in Millipore Sigma Water Filtration Systems?
High NWP in Millipore Sigma Water Filtration Systems can be caused by damage to the membrane or cassette, requiring an integrity test of the cassette. It may also be due to the system and cassette being over-pressurized, in which case you should reduce the system pressure. Another reason could be a worn cassette, which would necessitate its replacement.
What to do if there are tube fitting leaks in Millipore Sigma Pellicon 3 Cassettes?
If you notice tube fitting leaks in your Millipore Sigma Water Filtration Systems, several factors could be responsible. The tube or fitting might be cracked, necessitating inspection and replacement of the part. An NPT fitting might not be properly wrapped; in this case, remove the old tape and re-tape adequately with PTFE tape. The end of the tubing might not be cut squarely, requiring you to cut the tube square and reinstall it. A missing O-ring or ferrule on the fittings or a defective sanitary gasket could also be the cause, so replace the missing component, gasket, or the entire fitting. A loose clamp simply needs tightening, while an oversized clamp should be replaced with a smaller diameter clamp.
Why is there a leak between the holder and filters in my Millipore Sigma Pellicon 3 Cassettes?
If you observe a leak between the holder and filters in your Millipore Sigma Water Filtration Systems, it could be due to dirt or debris in the filter. To resolve this, disassemble the stack and check for any debris. Another potential cause is compression force being too low, in which case you should check the torque and compressive force.
How to fix multiple leaks in the filter stack of Millipore Sigma Water Filtration Systems?
Multiple leaks in the filter stack of Millipore Sigma Water Filtration Systems can arise from improper torque or compressive force. To address this, check the torque procedure and retorque the system. Additionally, inspect the tie rods or bolts for any dirt or corrosion.
What causes a low NWP value in Millipore Sigma Water Filtration Systems?
A low NWP value in Millipore Sigma Water Filtration Systems can occur if the system is not vented properly, so ensure it is vented to remove air. It could also be due to the system and cassette not being completely flushed or cleaned, so flush and clean them thoroughly.
Why is the integrity test failing or retention low in my Millipore Sigma Pellicon 3 Cassettes Water Filtration Systems?
Integrity test failures or low retention in Millipore Sigma Water Filtration Systems can occur due to several reasons. It could be that some areas of the membrane are not completely wetted, in which case you should repeat the flushing procedure with water and retest. Another cause might be the absence of a manifold adapter plate, so ensure it is installed. Inadequate pump capacity during filter wetting can also lead to this issue, so consider using a larger pump. Insufficient compression of the filter stack, temperature changes since the last torque application, chemical incompatibility, membrane damage, or improper membrane selection can also be causes. Inspect the system compression components, torque the unit, and retest. Visually inspect the filter for damage and replace if necessary. ...
Describes the different types of membranes available for the filter holder.
Guidance on selecting an appropriate pump for operating Pellicon® 3 cassettes.
Recommends specific water types for optimal system performance.
Step-by-step guide for installing smaller Pellicon® 3 cassettes in their specific holder.
Instructions for installing larger Pellicon® 3 cassettes in benchtop holders.
Procedures for installing Pellicon® 3 cassettes in manual process-scale holders.
Steps for installing Pellicon® 3 cassettes in hydraulic process-scale holders.
Details on pressurizing and operating the Pellicon® 3 filter holder assembly.
Procedures for flushing and cleaning the system after shipping.
Steps to prepare the system and cassettes for processing via flushing.
Cleaning and flushing steps performed after product recovery for system maintenance.
Detailed steps for flushing the cassette and system piping with solutions.
Procedures for cleaning the system when exposed to process fluids.
Procedures for sanitizing Pellicon® 3 cassettes after cleaning.
Steps for removing pyrogens after cleaning and sanitization.
Methods for testing the integrity of Pellicon® 3 filter systems.
Procedure for establishing baseline and monitoring water permeability.
General| Brand | Millipore Sigma |
|---|---|
| Model | Pellicon 3 Cassettes |
| Category | Water Filtration Systems |
| Language | English |
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