Name: Analytik Jena Biometra TAdvanced Series
Brand: Analytik Jena
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Operating Manual

Biometra TAdvanced

High-performance thermal cycler for

DNA amplification by PCR

Table of Contents3
Basic Information9
User Manual Notes9
Intended Use10
Safety Instructions11
General Notes11
Safety Markings on the Biometra Tadvanced11
Technical Condition12
Requirements for the Operating Personnel12
Safety Instructions: Transport and Installation12
Safety Instructions - Operation13
General13
Safety Instructions: Protection against Explosion and Fire13
Safety Instructions: Electrical Equipment13
Handling of Samples, Auxiliary and Operating Materials14
Safety Instructions - Maintenance and Repair14
Behavior During Emergencies15
Function and Setup16
High Speed Thermoblock17
Fig. 1 the Biometra Tadvanced Thermal Cycler17
High Performance Smart Lid18
Display18
User-Specific Quick Start of Programs18
Easy Programming19
Linear Gradient Tool19
GLP Compliance19
Open System Philosophy20
Order Numbers21
Installation and Commissioning22
Scope of Delivery22
Unpacking and Inspection22
Setting the Operating Voltage22
Fig. 2 Voltage Selector Switch on the Underside of the Device22
Commissioning23
General Setup23
Installation When Used in a Network23
Control Elements25
Biometra Tadvanced Front View25
Biometra Tadvanced Rear View25
Fig. 3 Front View of the Biometra Tadvanced25
Fig. 4 Rear View of the Biometra Tadvanced25
Quick Block Exchange26
High Performance Smart Lid (HPSL)26
Closing the Lid26
Fig. 5 Quick Block Exchange26
Opening the Lid27
Fig. 6 Placement of Sample Tubes in Different Block Systems27
The Biometra Tadvanced Software28
Keyboard28
Fig. 7 Keyboard28
Keypad29
Cursor Keys29
Confirm or Cancel29
Fig. 8 Keypad29
List of Commands and Icons Used30
Operation35
Power on Self-Test35
Login Screen35
Fig. 9 Start Screen35
Login36
Fig. 10 Login Screen36
Fig. 11 Select User Screen36
Home Screen37
Fig. 12 Enter Password Screen37
Fig. 13 Home Screen37
Block Status38
Fig. 14 Block Status/Quick Start Button38
Quick Start Function39
Fig. 15 Program Quick Start Screen (Biometra Tadvanced Mono)40
Fig. 16 Program Quick Start Screen (Biometra Tadvanced Twin)41
Incubation Mode42
Fig. 17 Multiblock Selection Query42
Fig. 18 Incubation Mode Screen (Biometra Tadvanced Mono)43
Fig. 19 Incubation Mode Screen (Biometra Tadvanced Twin)44
Fig. 20 Multiblock Selection Query (1)45
Fig. 21 Multiblock Selection Query (2)46
Creating, Editing and Saving Programs47
Programming Modes47
Fig. 22 Spreadsheet Programming47
Fig. 23 Graphical Programming48
Creating a New Program/Using a Program Template49
Fig. 24 Program Overview Screen49
Fig. 25 Blank Program Template50
Assigning Program Names51
Setting the Heated Lid Temperature51
Fig. 26 Program Template Screen51
Preheating the Heated Lid52
Editing Steps52
Fig. 27 Heated Lid Temperature Setting Screen52
Editing All Parameters of a Step53
Programming Loops54
Fig. 28 Program Step Editing Screen54
Programming a Temperature Increment55
Programming a Time Increment55
Fig. 29 PCR Program with a Loop55
Adjusting the Ramp Rate56
Programming a Gradient Step56
Fig. 30 Temperature Gradient on a 96 Well Sample Block57
Fig. 31 Linear Gradient Tool Screen (Biometra Tadvanced Mono)58
Fig. 32 Standard Gradient Programming Screen (Biometra Tadvanced Mono)58
Fig. 33 Temperature Gradient on a 48 Well Sample Block59
Fig. 34 Linear Gradient Tool Screen (Biometra Tadvanced Twin)60
Fig. 35 Standard Gradient Programming Screen (Biometra Tadvanced Twin)60
Direct Programming of Program Parameters for a Step61
Fig. 36 Temperature Gradient Query61
Fig. 37 Spreadsheet Program View61
Fig. 38 Graphical Program View62
Fig. 39 Individual Program Parameter Editing63
Fig. 40 Gradient View (Biometra Tadvanced Twin)63
Inserting a Step64
Deleting a Step64
Saving the Program64
Fig. 41 Program Overview Screen65
Fig. 42 Quick Selection Screen66
Starting, Coping and Deleting Programs67
Starting a Program67
Fig. 43 Program Overview Screen67
Fig. 44 Program Overview Screen with Preview68
Fig. 45 Twinblock Selection Query68
Copying a Program69
Copying All Programs70
Fig. 46 Program Overview Screen70
Deleting a Program71
Fig. 47 Program Overview Screen71
Deleting All Programs72
Fig. 48 Confirmation Prompt72
Fig. 49 Confirmation Prompt73
Running, Pausing, Continuing and Stopping Programs74
Display During a Run74
Fig. 50 Graphical View74
Fig. 51 Spreadsheet View75
Fig. 52 Display During the Run in a Graphical, Spreadsheet and Gradient View75
Fig. 53 Graphical View76
Fig. 54 Spreadsheet View76
Pausing a Program77
Fig. 55 Display During the Run in a Graphical, Spreadsheet and Gradient View77
Fig. 56 Spreadsheet View78
Fig. 57 Display Screen During a Program Pause (Graphical View)78
Fig. 58 Spreadsheet View79
Fig. 59 Display Screen During a Program Pause (Graphical View)79
Continuing the Program80
Skipping a Step80
Stopping the Program80
Fig. 60 Confirmation Prompt81
Fig. 61 Twinblock Selection Query81
Fig. 62 Confirmation Prompt81
Protocol Wizard82
Select Polymerase82
Fig. 63 Select Polymerase Screen82
Enter a New Polymerase or Edit a Polymerase83
Fig. 64 Edit Polymerase Screen83
Delete a Polymerase84
Fig. 65 Select Polymerase Screen84
Fig. 66 Security Query84
Protocol Wizard Parameter Screen85
Fig. 67 Protocol Wizard Parameter Screen86
Fig. 68 Protocol Wizard View Parameter Screen86
Primer Annealing Temperature Calculator87
Fig. 69 Security Query87
Fig. 70 Primer Annealing Temperature Calculator Screen88
Fig. 71 Edit Primer Concentration Screen89
Tools91
Configuration91
Fig. 72 Tools Screen91
Setting the Date and Time92
Fig. 73 Settings Screen92
Automatic User Logout93
Fig. 74 Date and Time Entry Screen93
Configuring the Beeper94
Fig. 75 Automatic User Logout Screen94
Network95
Fig. 76 Beeper Configuration Screen95
Fig. 77 Network Settings Screen, IP Settings Via Static96
Fig. 78 Network Settings Screen, IP Settings Via DHCP96
Display Brightness97
Fig. 79 Display Brightness Adjustment Screen97
Screen Calibration98
Factory Settings98
Fig. 80 Calibration Screen98
User Management99
Fig. 81 Confirmation Prompt99
Fig. 82 User Management Screen100
Fig. 83 Configure User Management Screen100
Creating a User101
Editing User Settings102
Fig. 84 Create New User Screen102
Fig. 85 User Data Screen103
Fig. 86 User Properties Screen104
Delete User105
Documentation105
Fig. 87 Confirmation Prompt105
Run Log File106
Fig. 88 Documentation Screen106
Fig. 89 Run Log File Overview Screen106
Fig. 90 Run Log File Screen107
Fig. 91 Program View Screen108
Power on Logfile109
Extended Self-Test Log File109
Fig. 92 Power on Log File Screen109
Error Log File110
Fig. 93 Extended Self-Test Log File Screen110
Fig. 94 Error Log File Screen110
Extended Self-Test111
Fig. 95 Sample Block Loaded with Plasticware for the Extended Self-Test112
Fig. 96 Extended Self-Test Screen112
Fig. 97 Extended Self-Test Overview Screen (Biometra Tadvanced Mono)113
Fig. 98 Extended Self-Test Overview Screen (Biometra Tadvanced Twin)113
Service Info File (SINF)114
Backup114
Fig. 99 Service Info File Creation Screen114
Cycler Information115
Fig. 100 Backup File Screen115
Contact116
Fig. 101 Cycler Info Screen116
Fig. 102 Service Department Contact Details Screen116
Adaptation of Programs117
Quick Reference Guide118
Fault Removal123
Administrator Password Forgotten123
Slow Heating and Cooling123
Auto Restart123
Auto Restart Without an Apparent Cause123
Adaptation of Programs from Other Thermal Cyclers124
Loosening the Lid Wheel in Case of Blockage124
Recommendations for the Use of 384 Well Sample Blocks124
Maintenance and Care126
Cleaning the Housing126
Disinfecting the Device127
Firmware Update127
Transport128
Device Return Information128
Packing the Biometra Tadvanced129
Disposal130
Specifications131
Model Specific Data131
Specifications for All Models137
Declaration of Conformity138
Index139

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Analytik Jena Biometra TAdvanced Series Specifications

General

Brand	Analytik Jena
Model	Biometra TAdvanced Series
Category	Laboratory Equipment
Language	English

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Analytik Jena Biometra TAdvanced Series User Manual

Table of Contents

Questions and Answers:

Analytik Jena Biometra TAdvanced Series Specifications

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