!
!
Introdu ct io n'
H
2
!and!CH
4
!are!generated!in!the!intestinal!lu men!by!bacterial!action!on!carbohydrates!in!the!small!or!
large!intes tin e .!O n c e!t h e!re s u lta nt !H
2
!and!CH
4
!is!diffuse d !in to !th e !b loo d s tre a m !it !is!t ra ns p o rte d !to !
the!alveoli!and!the n!ca n!be !dete cte d!in!ex pirato ry!air.!Levitt
1
!demonstrated!the!correlation!between!
intestina l!lumen!H
2
!and!CH
4
!production!and!H
2
!and!CH
4
!excretion!in!expiratory!air.!A ccurate!
measurement!of!H
2
!and!CH
4
!in!parts!p e r!million!(ppm)!in !ex p ira to ry!a ir!r ev ea ls !in to le ran c e!a n d /o r !
malabsorption!of!carbohydrates;!or!bacterial!overgrowth.!
The!GastroCH
4
ECK™!Gastrolyzer®!also!measures!O
2
!levels!in!t he !b re a th !sa mple!in!order!to!c o rre ct !fo r!
any!tests!that!do !not!achieve!an!end-tidal!breath!sam ple .!The !end -tid al!bre ath !sam ple !is!that!last!
portion!of!expired!air!and!contains!the!most!accurate!levels!of!H
2
!and!CH
4
.!End-tidal!bre ath !con tain s!
approx.!14-16%!O
2
!and!therefore!correction s!to!the!final!result!can!be!made!if!required!by!applyin g!a!
correction!factor!if!more!than!14%!O
2
!is!record ed !in !t he !s ample.!!
Operation!of!the!monitor!is!straightforward.!A!sampling!system !enables!end-expired!breath!to!be!
sampled!easily!and!hygienically,!using!single-use!disposable!mouthpieces!and!sing le-use!disposable!
face!masks.!!
!
Safety'Notes''
To!avoid!electric!shock,!this!equipment!must!be!connected!to!a!mains!supply!with!protective!earth.!!
The!operator!should!not!touch!the!patient!whilst!in!contact!with!either!the!computer!or!the!U SB!
connector!parts.!!
The!GastroCH₄ECK™!Gastrolyzer®!should!only!be!con nected!to!a!com pu ter!that!is!manufactured!in!
accordance!with!EN!60950!–!Safety!of!information!technology!equipment.!!
Please!do!not!attem pt!to!modify!the!equipment!in!any!w ay!or!use!accessories!not!specified!for!use!
by!the!manufacturer.!Any!attempt!to!do!so!will!invalidate!the!w arranty!and!may!affect!the!safety!of!
the!device.!!
Any!modification!to!this!equipm ent!during!the!actual!service!life!requires!evaluation!to!the!
requireme nt!of!E N!60 60 1-1!
!
Contraindications''
If!exhalin g!g e n tly !to !p r o duce!a!breath!sample!is!physically!demanding!then!it!may!cause!
contraindications!in!patients!who!have!had!a!recent!myocardial!infarction.!Also!extensive!exhalation!
might!lead!to!syncope.!
!