93-9005-00 ADView 2 User Manual | 29
September 1, 2016
Again, R is the ratio of two arterial pulse-added absorbance signals and its value is used to find the saturation SpO
2
in
an empirically derived equation into the oximeter’s software. The values in the empirically derived equation are based
upon human blood studies against a laboratory co-oximeter on healthy adult volunteers in induced hypoxia studies.
The above equations are combined and a noise reference (N’) is determined:
N’ = S(660) - S(905) x R
If there is no noise N’ = 0: then S(660) = S(905) x R which is the same relationship for the traditional pulse oximeter.
The equation for the noise reference is based on the value of R, the value being sought to determine the SpO
2
. The
MS board software sweeps through possible values of R that correspond to SpO
2
values between 1% and 100% and
generates an N’ value for each of these R-values. The S(660) and S(905) signals are processed with each possible N’
noise reference through an adaptive correlation canceler (ACC) which yields an output power for each possible value
of R (i.e., each possible SpO
2
from 1% to 100%). The result is a Discrete Saturation Transform (DST™) plot of relative
output power versus possible SpO
2
value as shown in the following figure where R corresponds to SpO
2
= 97%:
The DST plot has two peaks: the peak corresponding to the higher saturation is selected as the SpO
2
value. This
entire sequence is repeated once every two seconds on the most recent four seconds of raw data. The MS board
SpO
2
therefore corresponds to a running average of arterial hemoglobin saturation that is updated every two
seconds.
Masimo
Graphical Plot:
Below is a graphical plot of discreet A
RMS
values measured with Masimo SET Oximetry in a clinical study using
DCI/DCIP pulse oximetry sensors: