PlateLoc Thermal Microplate Sealer
Frequently asked questions
16 Reference for Optimal Thermal Microplate Sealing
Edge effects
Q
We are trying to seal microplates for an ELISA assay and are concerned about
potential edge effects. Any suggestions on how to reduce or eliminate the
problem?
A
Edge effects, such as variability in the sample data due to well- to- well
differences in evaporation, can be a challenge. Rather than optimize the
microplate or sealing parameters, some labs don’t use the sample wells in the
outer rows of the microplate, although this impacts both cost and throughput.
Microplate manufacturers are incorporating new microplate design features to
help reduce or eliminate the problem. Experimenting with these new designs
may improve your results and throughput, providing they meet the key sealing
criteria previously discussed—for example, having raised sample- well chimneys.
Application Support
Q
We have additional questions and need help with our applications. How can we
request help?
A
To help expedite your support request, you can complete and submit the
Request for PlateLoc Sealer Application Support.
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