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Agilent Technologies 7500 ICP-MS User Manual

Agilent Technologies 7500 ICP-MS
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Agilent 7500 ICP-MS
ChemStation (G1834B)
Operators Manual

Table of Contents

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Agilent Technologies 7500 ICP-MS Specifications

General IconGeneral
TypeInductively Coupled Plasma Mass Spectrometer (ICP-MS)
Mass Range2 to 260 amu
Ion SourceInductively Coupled Plasma (ICP)
RF Generator Frequency27.12 MHz
Dynamic Range9 orders of magnitude
Detection LimitSub-ppt levels
Sample Introduction SystemStandard nebulizer and spray chamber
Data AcquisitionMulti-channel
SoftwareAgilent MassHunter
DetectorDiscrete dynode electron multiplier
CoolingWater-cooled
RF PowerUp to 1600 W
Auxiliary Gas Flow0-2 L/min
Nebulizer Gas Flow0.6-1.2 L/min
InterfaceSampler and skimmer cones
Vacuum SystemTurbomolecular pumps
Isotope Ratio Precision<0.1% RSD

Summary

1 Preface

Who Should Read This Book

Identifies the target audience and required background for the manual.

How to Use This Book

Outlines the manual's structure and chapter contents for effective learning.

Conventions Used in This Book

Explains the typographical and formatting conventions used throughout the document.

Where to Go for More Information

Lists additional resources like hardware manuals and online help for further details.

1 Using the Agilent 7500 ICP-MS ChemStation Software

Accessing and Exiting the Software

Details the procedures for starting and closing the ChemStation application and its main window.

Moving within the Software

Explains navigation techniques using the mouse and moving between software windows.

Using the Command Line

Describes how to enable and use the command line for macro creation and customization.

2 Configuration

Configuring the ChemStation Software

Guides users through setting up software parameters and system configurations via the Configuration task.

Setting the sample introduction

Details how to configure sample introduction types like peristaltic pump, ISIS, or LC/GC/Laser Ablation.

3 Startup, Shutdown and Status

Starting the Instrument

Provides procedures for starting the Agilent 7500 from various states (unplugged, shutdown, standby).

Shutting Down the Instrument

Explains how to safely return the Agilent 7500 to Standby or Shutdown mode.

Checking the Instrument Status

Describes methods for monitoring instrument status using the Control Diagram and Meter Control Panel.

4 Tuning

Tuning for Sensitivity (Agilent 7500a)

Guides on tuning for optimal sensitivity using a recommended tuning solution.

Reducing Oxide Ions

Explains how to identify and reduce oxide ion signals during tuning procedures.

Tuning the ShieldTorch (High Sensitivity mode)

Provides instructions for tuning the ShieldTorch in high sensitivity mode.

Autotune

Describes the automated optimization of tunable lens and voltage settings for the instrument.

5 Creating a Method

Creating a Method Using the Method Wizard

Guides users through creating methods using an automated wizard, selecting application and sample types.

Setting the Acquisition Mode

Explains the six available acquisition modes for method creation, with Spectrum mode as default.

Setting Acquisition Parameters

Details how to set acquisition parameters for various modes like Spectrum, TRA, Time Program, and Isotope Analysis.

Creating/Editing Interference Correction Equations

Explains how to modify or edit interference correction equations for elements subject to interference.

6 Setting Up a Sequence

Creating a Sequence

Details the process of creating a sequence using the Sample Log Table for automated sample analysis.

Simulating a Sequence

Explains how to check a sequence before running it for potential issues like file name conflicts or disk space.

Modifying a Sequence

Explains how to modify a sequence by editing the Sample Log Table or sequence options.

7 Chained Sequence

Creating a Chained Sequence

Describes how to create a chained sequence to run multiple sequences sequentially.

Saving the Chained Sequence

Guides on saving the chained sequence to disk with a specified name.

8 Running a Sample Analysis

Running Samples by Using a Sequence

Explains how to run samples automatically by loading and executing a sequence.

Running Samples Manually

Explains how to run samples one at a time using a chosen method, potentially for efficiency.

Monitoring a Run

Describes how to view and monitor the progress of an ongoing analysis run in real-time.

Stopping a Run

Provides methods for stopping an active run from various points within the software.

9 Viewing Spectra

Displaying Spectra

Details how to display acquired spectral data and load appropriate data files for analysis.

Changing the Display Type

Explains options for changing spectral display type, axis scales, and graphic modes.

Analyzing Spectra

Describes how to use element databases and templates to identify unknown peaks in spectra.

10 Viewing a Time Chart

Displaying a Time Chart

Explains how to display time charts from acquired data using Time Resolved Analysis or Time Program modes.

Changing the Chart Type

Details how to view extracted ion charts and change chart display properties.

Analyzing Results Using a Time Chart

Explains how to define integration parameters and integrate peaks in a sample for concentration values.

11 Creating Custom Reports/Database

Creating a Custom Report

Explains how to create custom reports with specific information and layouts.

Creating a Custom Report Database

Explains how to create and format custom databases for analysis results.

Saving the Template

Guides on saving report or database files as templates for reuse.

12 Performing a Quantitative Analysis

Running Calibration Standards

Details the process of preparing and analyzing calibration standards for quantitative analysis.

Generating a Calibration Curve

Guides on creating calibration curves using data files from analyzed standards.

Setting the Internal Standard Correction

Details how to set internal standards to normalize instrument response for improved accuracy.

Blank Subtraction

Guides on subtracting a blank data file from sample data files to correct for background.

13 Performing a Semiquantitative Analysis

Performing a Semiquantitative Analysis

Explains how to obtain concentration information for elements without external calibration.

Entering Concentration Values

Details how to enter concentration values for calibration elements for semiquantitative analysis.

Using Internal Standard Correction

Details how to make internal standard corrections for semiquantitative analysis to compensate for matrix effects.

14 Performing an Isotope Ratio Analysis

Setting Isotope Ratio Parameters

Guides on setting parameters for isotope ratio analysis, including mass bias correction and isotope selection.

Generating an Isotope Ratio Analysis Report

Explains how to generate isotope ratio reports automatically or manually.

15 Performing an Isotope Dilution Analysis

Setting Isotopic Dilution Analysis Parameters

Guides on entering parameters for isotope dilution analysis, including mass bias and spike information.

Generating an Isotope Dilution Analysis Report

Explains how to generate isotope dilution analysis reports.

16 Tools Menu

DoList

Explains how to generate multiple reports for multiple data files and select report options.

Configure DoList

Details how to select and configure report options for the DoList tool.

17 DataBase Editor

Editing the Database

Explains how to edit elements, polyatomic molecules, and their properties within the database.

Using the Molecular Database Editor

Details how to enter or change information about elements or polyatomic molecules using the editor.

18 Installing the Agilent 7500 ChemStation Software (Windows XP)

Windows XP Configuration

Details essential BIOS and display settings required before software installation on Windows XP.

I/O Library Setup

Guides on installing the SICL driver and configuring I/O interfaces for the instrument.

Changing Windows Firewall Settings to Run ICP-MS ChemStation Under Windows XP SP2

Explains how to configure Windows Firewall to enable program and port communications for ChemStation.

19 Installing the Agilent 7500 ChemStation Software (Windows 2000)

Windows 2000 Configuration

Details essential BIOS and display settings for Windows 2000 configuration.

I/O Library Setup

Guides on installing the SICL driver and configuring I/O interfaces for Windows 2000.

BootP Service Setup

Details the configuration of BootP service for network communication under Windows 2000.

20 Appendix

Appendix A

Lists ChemStation menus and commands for quick reference.

Appendix B

Includes descriptions and equations for calibration, quantitation, and averaging.

Appendix C

Describes the process and calculation for dead time calibration.

Appendix D Compression and Decompression of Files

Explains how to compress and decompress files for troubleshooting and archiving.

Appendix E Precautions on Using the ICP-MS ChemStation with the LC/GC ChemStation

Provides precautions for connecting and installing software when using ICP-MS with LC/GC.

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