EasyManua.ls Logo

Leica BOND-PRIME User Manual

Leica BOND-PRIME
211 pages
To Next Page IconTo Next Page
To Next Page IconTo Next Page
Page #1 background imageLoading...
Page #1 background image
BOND-PRIME
FULLY AUTOMATED IHC AND ISH STAINING SYSTEM
USER MANUAL
A D V A N C E D S T A I N I N G I N S T R U M E N T S
(NOT for use in China)

Table of Contents

Question and Answer IconNeed help?

Do you have a question about the Leica BOND-PRIME and is the answer not in the manual?

Leica BOND-PRIME Specifications

General IconGeneral
BrandLeica Biosystems
ModelBOND-PRIME
Slide Capacity30 slides
ThroughputUp to 30 slides per run
Power Requirements100-240 VAC, 50/60 Hz
SoftwareBOND software
Operating Humidity20-80% non-condensing
TypeAutomated IHC & ISH Stainer
Weight220 kg
Operating Temperature18-30°C

Summary

Legal Notices

Trademarks and Copyright

Trademarks and copyright information for the manual.

Product Identification and Manufacturer

Document number and manufacturer details.

Important Information for Users

General user information and website.

Terminology and User Information

Intended Users

Defines target audience and required training.

Installation, Repairs, and Incident Reporting

Guidelines for installation, repairs, and incident reporting.

Data Security and Privacy Statement

Statement on personal data security and privacy.

Regulatory Notices

Intended Purpose

Describes the system's use in diagnostics.

FCC and CE Compliance

Details FCC and CE mark compliance.

IVD Equipment Instructions

Compliance with IVD standards.

Glossary of Symbols

Regulatory Symbols

Explains regulatory symbols used on product labeling.

ISO 15223-1 Symbols

Symbols for medical device labeling as per ISO 15223-1.

Glossary of Symbols (continued)

Equipment Symbols (ISO 7000 & IEC 60417)

Graphical symbols for equipment.

Other Symbols and Markings

Regulatory Marks (Prescription Only, CE, RCM, RoHS)

Various regulatory marks and directives.

Waste Electrical and Electronic Equipment (WEEE) Directive

Disposal guidelines for electronic waste.

Restriction of Hazardous Substances (RoHS 2)

Hazardous substance limits and recycling info.

Other Symbols and Markings (continued)

RoHS 2, FCC, UL, CSA, Intertek Compliance

Compliance marks and testing agency certifications.

Humidity and Unconnected Port

Specifications for humidity and port status.

Safety Symbols

ISO 7010 Safety Signs

Graphical symbols for safety signs per ISO 7010.

Safety Symbols (continued)

General Warnings

Notifications of hazards and safety precautions.

Instrument Operation Instructions

Guidelines for correct instrument operation.

Electrical Hazards

Chemical Hazards

Mechanical Hazards

Processing Module Operation Guidelines

General Cautions

Personal Protective Equipment (PPE)

Installation and Operational Hazards

Reagent Hazards

BOND-PRIME Hardware Overview

About the BOND System

Overview of the BOND System components.

The BOND-PRIME Processing Module

Detailed description of the processing module.

The Hood Components

Description of the module's hood components.

Preload and Unload Drawers

Description of slide loading/unloading drawers.

BOND System Ancillary Materials and Consumables

BOND-PRIME Processing Module Views

Front View

Visual representation of the module's front.

Rear View

Visual representation of the module's rear.

The Hood Components

Touchscreen Interface

Interface for controlling the module.

Viewing Window and Barcode Scanner

Window for observation and scanner for reagents.

Power Button and Hood Handle

Module power control and hood operation handle.

Preload and Unload Drawers

Preload Drawer Description

Drawer for loading slides.

Unload Drawer Description

Drawer for unloading slides.

Drawer and Waste System Components

Slide Drawer Inserts

Inserts for holding slides in drawers.

Drawer and Waste System Components (continued)

Waste Drains, Sumps, and Pickup Filter

Components for waste drainage and extraction.

Reagent Platform

Reagent Tray Types (Single & Dual)

Trays for holding reagent containers.

Reagent Platform Description

The main platform for reagent trays.

Bulk Containers

DI Water, Alcohol, and Solutions Containers

Containers for DI water, alcohol, and solutions.

Waste and Hazardous Waste Containers

Containers for bulk and hazardous waste.

Reservoir Cabinet

Reservoir Types and Capacities

Identifies reservoirs for DI water, vacuum, waste, etc.

AC Power Switch

Reagent Trays

Single Reagent Tray Capacity

Holds up to 5 reagent containers.

Dual Reagent Tray Capacity

Holds up to 10 reagent containers.

Work Surface Components (under the Hood)

High-Speed Robot

Robot for slide handling.

Wash Robots

Robots for washing ARC modules.

ARC Modules and Wash/Prime Stations

Modules for staining and washing/priming.

Mixing Well Plate and Slide Prep Station

Reagent mixing and slide preparation stations.

Work Surface Components (Front View)

High-Speed Robot and Wash Robots

Robot for slide handling and wash robots.

ARC Modules and Wash/Prime Stations

Modules for staining and washing/priming.

Mixing Well Plate and Slide Prep Station

Reagent mixing and slide preparation stations.

High-Speed Robot Components

ID Imager and Suction Cup

Components for slide identification and gripping.

ARC Probe and Bulk Reagent Probes

Probes for dispensing reagents.

Probe Selector Components

Tubing Connectors and Ferrules

Connectors and ferrules for tubing.

Compression Springs and Bulk Reagent Probes

Springs and probes for reagent dispensing.

Wash Robots

Wash Robot for Bank A

Wash robot for ARC Modules Bank A.

Wash Robot for Bank B

Wash robot for ARC Modules Bank B.

ARC Modules

ARC Module Latch and Cover

Latch and cover for accessing ARC modules.

ARC Module Lid and Covertile

Lid and cover for ARC module wells.

Wash/Prime Stations

Bulk Probe Prime Station

Station for priming bulk probes.

Wash Robot and ARC Probe Wash Stations

Wash stations for robots and probes.

Mixing Well Plate

Slide Preparation Station

Connecting and Powering On the Module

Disconnecting the Processing Module

Moving the Processing Module

Decommissioning and Disposal

Touchscreen Interface

Log In and Log Out Procedures

Procedures for user login and logout.

Navigation Bar Overview

Interface for navigating between screens.

Status Screen

Displays the module's current status.

Action Queue and Alert Banner

Manages system messages and alerts.

Log In and Log Out

Logging In

Steps to log into the touchscreen interface.

Logging Out

Navigation Bar

Status Screen Overview

Slides Loaded Segment

Shows loaded slides status.

Slides Processing Segment

Shows slides currently processing.

Slides Processing Complete Segment

Shows completed slides.

Action Queue Button

Button to access the action queue.

Slides Not Accepted Handling

Viewing Detailed Slide Information

Handling Unexpected Events

Action Queue and Alert Banner

Managing the Action Queue

Managing the display of system messages.

Completing Action Queue Tasks

Executing tasks from the action queue.

Hiding the Alert Banner

Hiding the alert banner.

Preloading Slides

Preload Screen Views

Preload Drawer View

Visualizing slide locations in the drawer.

Preload Case View

Visualizing slides by case.

Unloading Slides

Unload Screen Views

Unload Drawer View

Visualizing slide locations in the unload drawer.

Unload Case View

Visualizing slides by case in the unload drawer.

Detailed Case and Slide Information

Viewing Individual Slide Details

Displaying details for individual slides in a case.

Stopping Slide Processing

Procedure to stop a slide processing.

Reagents Screen

Preparing Reagent Containers and Trays

Steps to prepare reagent containers and trays.

Loading Reagent Trays

Reagent Icon Examples

Reagent System Icons

Visual examples of reagent system icons.

Reagent Container Icons

Visual examples of container icons.

Viewing Reagent System and Container Details

Unloading Reagent Trays

Maintenance Screen

Quick Start Guide

Introduction to Quick Start

Overview of the quick start chapter.

Starting the Processing Module

Steps to power on and initialize the module.

Loading Reagents and Detection System

Loading reagents and detection system.

Slide Processing Workflow (Preload, Process, Unload)

End-to-end slide processing workflow.

Starting the Processing Module

Loading Reagents and Detection System

Slide Processing Workflow

Cleaning and Maintenance Procedures

Maintenance Schedules

Guidelines for routine maintenance.

Refilling DI Water Container

Procedure to refill DI water.

Refilling Alcohol Container

Procedure to refill alcohol.

Refilling Lot Tracked Bulk Containers

Procedure to refill tracked containers.

Maintenance Schedules

Preventative Service Reminders

Reminders for preventative maintenance.

Cleaning and Maintenance Schedule

Schedule for cleaning tasks.

Periodic Maintenance Tasks (Two-, Four-, Six-Monthly, Notifications)

Cleaning and Maintenance Checklist

Refilling the DI Water Container

Refilling the Alcohol Container

Refilling Lot Tracked Bulk Containers

Emptying the Waste Containers

Using the BOND-PRIME Cleaning Kit

Starting Maintenance Mode

Wiping Internal ARC Module Surfaces

Wiping Reagent Platform and ARC Bank Surfaces

Cleaning the Suction Cup

Replacing the Suction Cup

Cleaning Drawer Inserts, Waste Drains, Sumps, and Pickup Filter

Cleaning Slide Drawer Inserts

Cleaning the inserts in the slide drawers.

Cleaning Waste Drains and Sump

Cleaning waste drains and sumps.

Cleaning Pickup Tube and Filter

Cleaning the pickup tube and filter.

Cleaning Wash/Prime Stations

Using the BOND-PRIME ARC Refresh Kit

Cleaning the Bulk DI Water Container

Cleaning Locked Bulk Reagent Containers

Cleaning Waste Containers

Cleaning the Sump Tray

Stopping Maintenance Mode

Shutting Down the Processing Module

Replacing Power Supply Fuses

Troubleshooting Guide

Failure to Initialize

Reasons for initialization failure.

Network Connectivity Error

Troubleshooting network connection issues.

Manually Retrieving Slides

Procedures for manual slide retrieval.

Removing Slide Fragments

Procedures for removing slide fragments.

Failure to Initialize

Network Connectivity Error

Manually Retrieving Slides from Processing Module

Retrieving Slides from Preload/Unload Drawers

Retrieving slides from drawers.

Retrieving Slides from Work Surface

Retrieving Slides from ARC Modules

Retrieving Slides During Power Failure

Removing Slide Fragments from ARC Modules

Product Specifications

System Specifications

Details about system components and software.

Physical Specifications

Dimensions, weight, and clearances.

Electrical Power and UPS Requirements

Power requirements and UPS.

Environmental Specifications

Operating temperature, humidity, and altitude.

System Specifications

Physical Specifications

Electrical Power and UPS Requirements

Environmental Specifications

Operating Specifications

Microscope Slide Specifications

Slide Label Specifications

Details on slide label dimensions.

Transport and Storage Specifications

Related product manuals