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Thermo Scientific EASY-nLC 1200 User Manual

Thermo Scientific EASY-nLC 1200
311 pages
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Thermo
EASY-nLC 1200
Troubleshooting and Maintenance Guide
Touch-screen application version 4.2
60053-97274 Revision C 2019

Table of Contents

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Thermo Scientific EASY-nLC 1200 Specifications

General IconGeneral
BrandThermo Scientific
ModelEASY-nLC 1200
CategoryLaboratory Equipment
LanguageEnglish

Summary

Preface

Related Documentation

Lists additional Thermo Fisher Scientific documents available for the EASY-nLC instrument.

Safety and Special Notices

Highlights essential safety practices and warnings for operating the instrument.

Contacting Us

Provides contact information for Thermo Fisher Scientific customer service and technical support.

Chapter 1 Introduction

Hardware Components

Detailed description of the instrument's physical components, including pumps, valves, and detectors.

Touch-Screen Application

Overview of the instrument's control interface and its functionalities for operation and maintenance.

Specifications

Lists performance and technical parameters of the EASY-nLC 1200 instrument.

Chapter 2 Maintenance Schedule

Daily Maintenance

Routine checks and tasks to be performed on a daily basis for instrument upkeep.

Quarterly Maintenance

Procedures to be performed every three months for instrument maintenance.

Yearly Maintenance

Annual maintenance tasks recommended for long-term instrument performance.

Field Service Repairs

Information on when to contact field service for complex instrument repairs.

Chapter 3 Maintenance Scripts and Service Records

Maintenance Scripts

Description of built-in scripts for instrument preparation and troubleshooting.

Keeping Service Records

Instructions on how to electronically log service actions performed on the instrument.

Checking and Resetting the Device Usage Counters

Procedure to view and reset instrument component usage counters.

Chapter 4 System Modifications

Ordering the UHPLC Liquid Junction Kit

Information on ordering the kit for using analytical columns with bare fused-silica ends.

Installing the Modified Column Out and Waste In Lines

Procedure for installing modified tubing lines provided in the UHPLC Liquid Junction Kit.

Chapter 5 Routine Maintenance

Maintaining a Clean Working Environment

Guidelines for keeping the instrument and its surroundings clean.

Using Only UHPLC/MS-Grade Solvents

Importance of using specific grade solvents to prevent system issues.

Maintaining the Syringe Pumps

Procedures for maintaining and replacing components of the instrument's syringe pumps.

Replacing the Autosampler Needle

Step-by-step guide for replacing the autosampler needle when bent or clogged.

Chapter 6 Field Service Maintenance

Replacing the Built-In Computer

Procedure for replacing the instrument's internal computer box.

Replacing the Pump

Instructions for replacing a pump component in the EASY-nLC instrument.

Replacing the Autosampler

Detailed steps for removing and installing the autosampler unit.

Replacing the Monitor

Procedure for replacing the instrument's touch-screen monitor.

Chapter 7 Troubleshooting

Troubleshooting Tips

General guidance and pointers for diagnosing and resolving instrument issues.

Autosampler Problems

Common issues related to the autosampler operation and their solutions.

Troubleshooting a Pump That Fails the Flush Air Script

Step-by-step guide to diagnose and fix pumps failing the Flush Air script.

Troubleshooting a Pump That Fails the Leaks Script

Procedure to identify and resolve issues causing pumps to fail the Leaks script.

Running a System Leak Test

Instructions for performing a system-wide leak test to identify and locate leaks.

Troubleshooting a System Blockage

Diagnosing and resolving blockages within the instrument's solvent pathways.

Troubleshooting Communication Problems

Resolving issues related to network connectivity and instrument communication.

Chapter 8 Calibrating the Autosampler’s XYZ Robot

Replacing the Autosampler Adapter Plate

Procedure for replacing the autosampler's tray adapter plate.

Managing Plate Formats

Instructions for using, creating, or deleting plate formats for the autosampler.

Calibrating Plates

Steps to determine XYZ coordinates for vial or well positions on plates.

Calibrating the Wash Bottle and Extra Vial Positions

Procedure to calibrate the positions of wash bottles and extra vials.

Chapter 9 Remote Support

Connecting the EASY-nLC Instrument to the Support Server

Steps to establish a remote connection for technical support and firmware updates.

Saving System Files on a USB Removable Storage Device

Procedure to copy system files to a USB device for backup or transfer.

Downloading the Latest Firmware File

Instructions for installing the latest firmware for the touch-screen application.

Chapter 10 Returning the EASY-nLC Instrument

Transport Instructions

Procedures for preparing the instrument for shipment or return.

Appendix A Error Codes

Appendix B Mobile Phase Viscosity

Appendix C Consumables and Replacement Parts

Ordering Information

Website and details for ordering spare parts and accessories for the EASY-nLC instrument.

Solvent System Schematic for the EASY-nLC 1200 Instrument

Diagram illustrating the flow lines and components of the solvent system.

Common Replacement Parts

List of frequently used replacement parts and their recommended inventory.

Appendix D Quick Reference Guides for Routine Maintenance

Using nanoViper Fittings Quick Reference Guide

Condensed guide for connecting and using nanoViper fittings.

Maintaining the Pump Quick Reference Guide

Condensed guide for routine maintenance procedures related to the instrument pumps.

Replacing a Damaged Autosampler Needle

Condensed guide for replacing a damaged autosampler needle.

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