ATS 3210 - Page 34

30 Series 31XX, 32XX Furnaces | Appendix A: SDS Information
6
10. STABILITY AND REACTIVITY
(a) Reactivity
RCF is non-reactive.
(b) Chemical stability
A
s supplied RCF is stable and iner
t
.
(c) Possibility of hazardous reactions
None
(d) Conditions to avoid
Please refer to handling and storage advice in Section 7
(e) Incompatible materials
None
(f) Hazardous decomposition products
Thermal decomposition of binder from fires or from first heat of product may
release smoke, carbon monoxide, and carbon dioxide. Use adequate ventilation
or other precautions to eliminate exposure to vapors resulting from thermal
decomposition of binder. Exposure to thermal decomposition fumes may cause
respiratory tract irritation, bronchial hyper-reactivity or an asthmatic-type
response.
11. TOXICOLOGICAL INFORMATION
For more details on scientific publications referenced in this SDS see http://ww
w
.htiwcoalition.org/publications.html
(a) through (d)
TOXICOKINETICS, METABOLISM AND DISTRIBUTION
Basic Toxicokinetics
Exposure is predominantly by inhalation or ingestion. Man-made vitreous fibers of a similar size to RCF have not
been shown to migrate from the lung and/or gut and do not become located in other organs of the body.
Human Toxicological Data/Epidemiology Data
In order to determine possible human health effects following RCF exposure, the University of Cincinnati has been
conducting medical surveillance studies on RCF workers in the U.S.
A
; this epidemiological study has been ongoing
for 25 years and medical surveillance of RCF workers continues. The Institute of Occupational Medicine (IOM) has
conducted medical surveillance studies on RCF workers in European manufacturing facilities.
Pulmonary morbidity studies among production workers in the U.S.
A
. and Europe have demonstrated an absence of
interstitial fibrosis. In the European study a reduction of lung capacity among smokers has been identified, however,
based on the latest results from a longitudinal study of workers in the U.S.
A
. with ove
r
17-year follow-up, there has
been no accelerated rate of loss of lung function (McKay et al. 2011).
A
statistically significant correlation between pleural plaques and cumulative RCF exposure was evidenced in th
e
U.S.
A
. longitudinal study.
The U.S.
A
. mortality study showed no excess mortality related to all deaths, all cancer, or malignancies or diseases of
the respiratory system including mesothelioma (LeMasters et al. 2003).
Information on Toxicological Effects

A
cute toxicit
y
: short term inhalation
No data available: Short term tests have been undertaken to determine fiber (bio) solubility rather than toxicity;
repeat dose inhalation tests have been undertaken to determine chronic toxicity and carcinogenicity.

A
cute toxicit
y
: oral
No data available: Repeated dose studies have been carried out using gavage. No effect was found.

Skin corrosion
/
irritation
Not a chemical irritant according to test method OECD no. 404.

Serious eye damage
/
irritation
Not possible to obtain acute toxicity information due to the morphology and chemical inertness of the substance.