28
Drug List
The pre-installed drug list offers the following values:
Drug / Parameter
V
1
[Litre]
Propofol Remifentanil
k
12
[min
-
1
] 0,112
0,119
k
13
[min
-1
] 0,0419
k
21
[min
-
1
] 0,055
k
31
[min
-1
] 0,0033
k
e0
[min
-1
] 0,26
Reference Marsh et al., Br.
J. Anaesthesia,
Vol. 67, 1991,
41-48
Effect-site
targeting
No
k
10
[min
-1
]
0,228
*
Weight
0,302 - 0,0056
*
(Age - 53)
0,443 + 0,0107
*
(Weight -
77) - 0,0159
*
(LBM - 59) +
0,0062
*
(Height - 177)
0,196
[1,29 - 0,024
*
(Age - 53)] /
[18,9 - 0,391
*
(Age - 53)
0,0035
0,456
Schnider et al., Anesthesio-
logy, Vol. 88, 1998, 1170-
1182 Schnider et al.,
Anesthesiology, Vol. 90,
1999, 1502-1516
Yes
4,27
[2,05 - 0,0301
*
(Age - 40)] /
[5.1 - 0.0201
*
(Age - 40) +
0.072 * (LBM - 55)]
[2,6 - 0,0162
*
(Age - 40) +
0,0191
*
(LBM - 55)] / [5.1 -
0.0201
*
(Age - 40) + 0.072 *
(LBM - 55)]
[0,076 - 0,00113
*
(Age - 40)] /
[5.1 - 0.0201
*
(Age - 40) +
0.072
*
(LBM - 55)]
[2,05 - 0,0301
*
(Age - 40)] /
[9,82 - 0,0811
*
(Age - 40) +
0,108
*
(LBM - 55)]
0.01402 - 0,0002085
*
(Age -40)
0,595 - 0,007
*
(Age - 40)
Minto et al., Anesthesiology,
Vol. 86, 1997, 10-33
Yes
5,1 - 0,0201
*
(Age - 40) +
0,072 * (LBM - 55)
Available Concentrations
Propofol Remifentanil
Default Max. Rate 1.200 ml/h
TCIProp
Hard Limit Rate Max of pump
Plasma Limit Default 400 %
Plasma Limit Hard Low 100 %
Plasma Limit Soft Max 450 %
Default Target 0.0 µg/ml
Target Soft Max 8.0 µg/ml
Short name
5 mg/ml
10 mg/ml
20 mg/ml
1.200 ml/h
TCIRemi
Max of pump
400 %
100 %
450 %
0.0 ng/ml
8.0 ng/ml
Target Hard Max 15.0 µg/ml 20.0 ng/ml
Decrement Concentration
Default
1.0 µg/ml 1.0 ng/ml
Default Parameter Set Marsh Minto
20 µg/ml
50 µg/ml
Chapter 3
SPECIAL FUNCTIONS