REPLIGEN XCell ATF10 User Manual

XCell
TM
ATF System with C410:V4B Controller User Guide
4
Note on the Exhaust Cycle:
WARNING
Glass bioreactors or single-use bioreactors (SUBs), unless otherwise specified by the
manufacturer of the vessel, should not be pressurized. Such vessels can explode if
pressurized.
If a vessel is being operated without positive pressure the XCell™ ATF requires a vacuum
(negative pressure) to move the diaphragm to its lowest position. The PA chamber can then be
alternately pressurized and evacuated to produce XCell™ ATF action while maintaining the
process vessel at atmospheric pressure.
Conversely, when using a vessel that that is operated under positive pressure, the vessel pressure
can be used to drive the liquid from the vessel to the PL chamber. When vessel pressure is
limited, it may be supplemented with vacuum. In either of the above schemes, one is driving the
liquid from the vessel to the Diaphragm Pump by increasing the pressure in the vessel relative to
the Diaphragm Pump. Even with positive vessel pressure assisting with diaphragm deflation,
vacuum is generally required to ensure proper ATF operation
WARNING
When using a glass vessel or SUB, be sure to maintain an unrestricted vent from the
vessel. In the case a diaphragm fails, the air flow into the Diaphragm Pump will proceed
through the HFM or SM into the vessel. A free exhaust from the vessel will minimize the
buildup of pressure in the vessel.

REPLIGEN XCell ATF10 Specifications

General

Brand	REPLIGEN
Model	XCell ATF10
Category	Laboratory Equipment
Language	English