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REPLIGEN XCell ATF10

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XCell
TM
ATF System
With C410:V4B Controller
USER GUIDE
XCell
ATF4 | XCell
ATF6 | XCell
ATF10

Table of Contents

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REPLIGEN XCell ATF10 Specifications

General IconGeneral
BrandREPLIGEN
ModelXCell ATF10
CategoryLaboratory Equipment
LanguageEnglish

Summary

XCell ATF System

Description of the XCell ATF System and Process

XCell ATF System Pump Cycle

Details the operational cycle of the XCell™ ATF system pump.

XCell ATF System Control Scope and Objectives

Outlines the control capabilities and goals of the XCell™ ATF system.

XCell C410 v4 B Controller Layout

Filtration Assembly (Stainless Steel)

Details the stainless steel filtration assembly components and connections.

Pneumatics Box (P-Box) Components

Lists and describes the components within the Pneumatics Box (P-Box).

Electrical Box (E-Box)

Details the components housed within the Electrical Box (E-Box).

Power Box (Power Separation) Components

Describes the components located in the Power Box for power separation.

Primary Pneumatic Services

Explains the primary pneumatic connections and services for the system.

Primary Electric Services

Details the primary electrical connections and services required for operation.

C410 v4 B Controller Process and Control

Control Overview

Provides a general overview of the process and control mechanisms.

Control Functional Algorithms

Explains the algorithms used by the controller for process management.

Interface and Screens

Describes the user interface and various screens of the controller.

Startup

Guides users through the initial setup and startup procedures for the system.

XCell ATF Hollow Fiber Module and Diaphragm Replacement

Sterilization

Preparation of Filtration Assembly for Autoclaving

Steps for preparing the filtration assembly before autoclaving.

Autoclave Cycle

Details the recommended autoclave cycle for sterilization.

Connection to Bioreactor (ATF-to-Bioreactor)

Hard Connection

Describes the procedure for making a hard connection to the bioreactor, including SIP.

Maintenance

Diaphragm

Recommendations for diaphragm usage, orientation, and lifespan.

Appendix 2: Access levels to the C410 v4 B controller

Appendix 4: Profinet Communication

Appendix 5: Profibus Communication

Appendix 6: Delta V Example configuration

Appendix 7: OPC Communication

Appendix 8: Audit Trail (If Equipped)

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