isoCAL:
Automatic Calibration, Adjustment
and Linearization
First set either
On and reset the
application, isoCAL
and linearization on 
or On without resetting
the app. (factory setting) in 
the “Setup: Balance/scale functions”
menu.  
The “isoCAL” display automatically
begins flashing if the ambient 
temperature changes in relation to the
temperature at the time of the last 
calibration/adjustment, or after a 
defined time interval has elapsed.  
The balance is telling you that it wants
to adjust itself.
This automatic calibration and adjust-
ment prompt is activated when:
– The change in temperature is greater
than1.5 Kelvin or the elapsed time 
interval is greater than 4 hours 
– The balance Setup mode is not active
– No number or letter input is active
– The load has not been changed within
the last 2 minutes
– The balance has not been operated 
within the last 2 minutes
– The load on the balance does not
exceed 2% of the maximum capacity.
– When you turn on the balance after 
it has been disconnected from power 
(only on verified balance)
When these requirements are met,
C is displayed in the line for measured
values.
If the balance is not operated and 
the load is not changed, internal 
calibration and adjustment will start
after 15 seconds have elapsed.
55
Automatic Calibration and Adjustment
at Set Times *
In the Setup menu, you can now enter
up to three different times of day for
automatic calibration/adjustment (see
menu tree on page 48).  When one 
of these times is reached, the balance
displays the flashing calibration prompt
(“isoCAL”).  Calibration/adjustment is
not performed if the balance is
– off (standby) or
– in the Setup mode at the time set for
calibration.
If the balance is being operated at 
the time set for automatic calibration/
adjustment, the calibration/adjustment
sequence will not  be prompted or 
performed afterwards.
Automatic calibration/adjustment 
is prompted at set times when:
– The set time is reached
– The balance Setup mode is not active
– No alphanumeric input is active 
(e.g., equation for calculation)
– The load has not been changed within
the last 2 minutes
– The balance has not been operated 
within the last 2 minutes
– The load on the balance does not
exceed 2% of the maximum capacity
* = does not apply to verified balances
In the Setup menu, you can configure
the balance so that after calibration and
adjustment
– the application program 
is restarted 
On and reset 
the application
– isoCAL and linearization are activated
and the application program must be
restarted
isoCAL and 
linearization on
– the application program remains at its
previous status 
On without resetting
the app.
Also in Setup, you can configure the
balance so that it displays a calibration
prompt, but does not perform the 
calibration/adjustment functions 
automatically:
Only adjustment prompt
Switching Off the isoCAL Function
on Balances Verified for the EU 
(exept for ME614S-0CE)**:
– This is done after Sartorius Customer
Service has modified the balance
> Afterwards, the balance can 
be used only within the limited legal
temperature range.
Limited temperature range:
– +15°C to +25°C (59°F to 77°F) 
(isoCAL off)
After unplugging the balance from AC
power, please observe the following 
– Calibrate/adjust right after turning on
the power, before resuming a weighing
operation
– calibrate/adjust after 30 minutes
– calibrate/adjust after 4 hours
You should calibrate/adjust the balance
at least once a day.
** including the Signatories of the Agree-
ment of the European Economic Area
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