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SP Scientific VIRTIS 2K - Freeze-Drying Concepts Explained; Overview and Elements of Freeze-Drying

SP Scientific VIRTIS 2K
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Rev 007, 10/11 v
© SP Scientific 2011
Contents
Important Symbols ............................................................................................................................................... ii
Freeze Dryer Safety Warnings ............................................................................................................................. ii
Warranty Information (VirTis Lyophilizers) .......................................................................................................... iii
Introduction ................................................................................................................. 1
Features ............................................................................................................................................................... 1
BenchTop Usage ................................................................................................................................................. 1
Cold Trap Condenser Module .............................................................................................................................. 1
Available Configurations ...................................................................................................................................... 2
Installation and Startup ............................................................................................... 3
Initial Inspection ................................................................................................................................................... 3
Service Connections ............................................................................................................................................ 3
Vacuum Pump Installation ................................................................................................................................... 4
Installing the Vacuum Pump ............................................................................................................................ 4
Oil Mist Eliminators .......................................................................................................................................... 5
BenchTop Setup .................................................................................................................................................. 5
Vacuum Baffle Plate ............................................................................................................................................ 6
Freeze-Drying Concepts ............................................................................................. 7
Overview .............................................................................................................................................................. 7
Elements of Freeze-Drying .................................................................................................................................. 7
Freeze ............................................................................................................................................................. 7
Vacuum ........................................................................................................................................................... 7
Heat ................................................................................................................................................................. 8
Condenser ....................................................................................................................................................... 8
Product Dependencies ......................................................................................................................................... 8
Sentry 2.0 Controls ..................................................................................................... 9
LED Wave Display (Qualitative Reference) ......................................................................................................... 9
Button Functions ................................................................................................................................................ 10
Up/Down (+/-) Buttons ................................................................................................................................... 10
MENU Button ................................................................................................................................................ 10
COND Button ................................................................................................................................................ 10
VAC Button .................................................................................................................................................... 10
AUTO Button ................................................................................................................................................. 10
DEFR Button ................................................................................................................................................. 10
LCD Display Functions ...................................................................................................................................... 11
Main Menu ......................................................................................................................................................... 11
Vacuum Control ............................................................................................................................................. 12
Purge ............................................................................................................................................................. 12
Bath ............................................................................................................................................................... 12
Heat (Optional) .............................................................................................................................................. 12
User Options Menu ............................................................................................................................................ 12
Vacuum Control ............................................................................................................................................. 12

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