NINA-B3 series - System integration manual 
UBX-17056748 - R13  Contents  Page 3 of 72 
C1-Public 
Contents 
Document information ................................................................................................................................ 2 
Contents .......................................................................................................................................................... 3 
1  System description ............................................................................................................................... 6 
1.1  Overview and applications ........................................................................................................................ 6 
1.2  Architecture ................................................................................................................................................. 8 
1.2.1  Block diagrams .................................................................................................................................... 8 
1.2.2  Hardware options ............................................................................................................................... 8 
1.2.3  Software options ................................................................................................................................ 8 
1.3  Pin configuration and function ................................................................................................................. 9 
1.4  Supply interfaces ........................................................................................................................................ 9 
1.4.1  Main supply input ............................................................................................................................... 9 
1.4.2  Digital I/O interfaces reference voltage (VCC_IO) ........................................................................ 9 
1.4.3  VCC application circuits .................................................................................................................... 9 
1.5  System function interfaces ....................................................................................................................10 
1.5.1  Module reset ......................................................................................................................................10 
1.5.2  Internal temperature sensor ..........................................................................................................10 
1.6  Debug – Serial Wire Debug (SWD) .........................................................................................................10 
1.7  Serial interfaces ........................................................................................................................................10 
1.7.1  Universal Asynchronous Serial Interface (UART) ......................................................................10 
1.7.2  Serial Peripheral Interface (SPI) .....................................................................................................11 
1.7.3  Quad serial peripheral interface (QSPI) ........................................................................................11 
1.7.4  I2C interface.......................................................................................................................................12 
1.7.5  USB 2.0 interface ..............................................................................................................................12 
1.8  GPIO pins .....................................................................................................................................................12 
1.8.1  Analog interfaces ..............................................................................................................................13 
1.9  Antenna interfaces ...................................................................................................................................14 
1.9.1  Antenna pin – NINA-B3x1 ................................................................................................................14 
1.9.2  Integrated antenna – NINA-B3x2/B3x6........................................................................................15 
1.9.3  NFC antenna ......................................................................................................................................15 
1.10 Reserved pins (RSVD) ..............................................................................................................................15 
1.11 GND pins .....................................................................................................................................................15 
2  Software ................................................................................................................................................ 16 
2.1  u-connectXpress software ......................................................................................................................16 
2.2  Open CPU ....................................................................................................................................................17 
2.2.1  Nordic nRF5 SDK ..............................................................................................................................17 
2.2.2  Zephyr .................................................................................................................................................21 
2.2.3  Saving Bluetooth MAC address and other production data ....................................................22 
2.2.4  Support – Nordic development forum ..........................................................................................23 
2.3  Updating NINA-B31 software .................................................................................................................23 
2.3.1  Updating over UART.........................................................................................................................23