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cytiva AKTA flux s User Manual

cytiva AKTA flux s
212 pages
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ÄKTA
flux s
Operating Instructions
Original instructions
ÄKTA flux
cytiva.com

Table of Contents

Questions and Answers:

cytiva AKTA flux s Specifications

General IconGeneral
UV MonitoringYes
Pressure RangeUp to 6 bar
ControlUNICORN software
Operating Temperature4°C to 40°C
pH Range2 to 12
UV Detection Wavelength280 nm
Power Requirements100-240 V, 50/60 Hz
Temperature Control Range5 to 40 °C (optional)

Summary

1 Introduction to ÄKTA flux s

1.1 Important User Information

Provides critical information for safe operation, intended use, and prerequisites.

1.2 About This Manual

Explains the purpose, scope, and typographical conventions used in the manual.

1.3 Associated Documentation

Lists related user documentation and software help resources for the system.

1.4 Additional User Documentation and Specific Documentation

Details system-specific documentation and component documentation for ÄKTA flux s.

1.5 Abbreviations Used in Documentation

Defines abbreviations used throughout the ÄKTA flux s user documentation.

2 Safety Instructions for ÄKTA flux s

2.1 Safety Precautions

Outlines general, personal, and environmental safety precautions for operating the system.

2.2 System Labels and Symbols

Describes the system label and other safety or regulatory labels attached to the product.

2.3 Emergency Procedures

Provides instructions for emergency shutdown and restarting the system after power failure.

3 System Description of ÄKTA flux s

3.1 Illustrations of ÄKTA flux s Components

Provides visual identification of front and rear views of the ÄKTA flux s system.

3.2 System Control Interface

Explains how the system is controlled via the operator touchscreen and main screen.

3.3 Standard Equipment Overview

Details the standard components of the ÄKTA flux s system.

3.4 Optional Equipment for ÄKTA flux s

Describes optional components that can be installed to enhance system functionality.

3.5 Filter Devices for ÄKTA flux s

Provides a description and overview of filter types that can be installed with the system.

3.6 Process Flowchart Illustration

Presents a flowchart detailing the process components and pressure sensors.

4 Flow Lines in ÄKTA flux s

4.1 Recirculation Loop Description

Explains the recirculation loop, including feed and retentate lines, flow control, and DeltaP.

4.2 Permeate Line Functionality

Describes the permeate line, its flow control, and recycling capabilities.

4.3 Transfer Line Setup

Details the transfer line, which requires an optional transfer pump for operation.

5 Installation of ÄKTA flux s

5.1 Site Requirements and Preparation

Summarizes power supply, environmental, and positioning requirements for installation.

5.2 Unpacking the ÄKTA flux s

Provides requirements for receiving, storing, and safety precautions during unpacking.

5.3 Transporting the ÄKTA flux s

Outlines important information and requirements for safely transporting the system.

5.4 Setting Up the ÄKTA flux s

Guides through the steps required to set up the ÄKTA flux s before initial use.

5.5 Installation Test Procedures

Lists the performance tests that must be conducted after the system installation.

6 Run Preparations for ÄKTA flux s

6.1 Filter Installation Procedures

Contains general information on where and how to install different filter types on the system.

6.2 Installing Kvick Lab Packet and Holder

Provides instructions for installing Kvick Lab packet holders with filters onto the system.

6.3 Filter Testing Procedures

Details pre-process procedures like filter integrity and leakage tests before product processing.

6.4 Calibration Procedures

Describes procedures for calibrating pumps, pressure sensors, and tank level for accuracy.

7 Operation of ÄKTA flux s

7.1 Starting the System

Guides through the initial steps and precautions for starting the ÄKTA flux s system.

7.2 Performing a Run

Details the procedures for performing basic filtration and automated features.

7.3 Procedures After Completing a Run

Outlines essential steps to empty, clean, and prepare the system after operation.

8 Settings and Configuration

8.1 USB Device Management and Software Update

Covers generating system health reports, managing USB devices, and updating software.

8.2 Configuring Alarms Screen

Explains how to set up system warnings and alarms for various parameters.

8.3 Configure System Screen Settings

Allows users to configure system parameter units like pressure, temperature, and flow rates.

8.4 Calibration Settings Screen

Interface for calibrating pumps, pressure sensors, and tank level.

8.5 System Information Screen

Displays installed software, running hours, and optional components status.

8.6 Setting System Set-points

Guides on how to adjust set-points for various system parameters like flow and level.

9 Maintenance of ÄKTA flux s

9.1 User Maintenance Schedule

Provides recommendations for routine and periodic maintenance tasks.

9.2 Sanitization and Cleaning Procedures

Details methods for sanitization and cleaning-in-place (CIP) of the system.

9.3 Storage Procedures

Describes procedures for both short-term and long-term storage of the system.

9.4 Repair and Calibration Guidance

Provides information on component repair and calibration, advising to contact support.

9.5 Replacing the Mains Fuse

Step-by-step instructions for safely replacing the main fuse of the instrument.

10 Troubleshooting Guide

11 Reference Information

11.1 System Specifications

Lists technical specifications including dimensions, weight, volume, and sound levels.

11.2 Software License Information

Details the software components and their associated license agreements.

11.3 Wetted Materials in ÄKTA flux s

Lists materials used in manufacturing and standard components that contact process fluids.

11.4 Chemical Resistance Guidelines

Provides allowed exposure concentrations and times for chemicals used with the system.

11.5 Recycling and Disposal Information

Describes procedures for decontamination, disposal, and recycling of the equipment.

11.6 Regulatory Information

Lists directives and standards fulfilled by the ÄKTA flux s system.

11.7 Ordering Information and Contact Details

Provides contact details and website for ordering information and spare parts.

11.8 Health and Safety Declaration Form

Form for service personnel and customers to declare equipment is clean and safe for access.

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