Device overview
10
Intended use
The device is an automatic sequencer for NGS applications.It is
intended to be used with specific validated reagents and analytical
software for decoding the DNAs or RNAs sequence of human clinical
sample prepared into specific sequencing libraries such as DNA
nanoball libraries.
The device is especially used by the personnel who has been trained
professionally.
Working principle
The device adopts the advanced DNA Nanoball (DNB) and the core
technology of combinatorial probe-anchor synthesis (cPAS) and
uses a regular arrayed flow cell with the special decorated surface.
Each decorated site of the flow cell contains a single DNB, and the
decorated site is evenly arranged on the flow cell, ensuring that the
optical signal of different Nanoball cannot be interrupted by each
other. Therefore, the accuracy of signal process is improved.
The following figure demonstrates how to make DNBs:
Ad-inserted
ss DNA circle
Replicate
DNA Nanoball (DNB)
N×
3×
2×
1×
DNBs
Figure 1 Making DNBs
To Next Page
Loading...