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PerkinElmer chemagic 360-D User Manual

PerkinElmer chemagic 360-D
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2024-0010 INSTRUMENT MANUAL
chemagic 360-D

Table of Contents

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PerkinElmer chemagic 360-D Specifications

General IconGeneral
TypeAutomated Nucleic Acid Extraction System
ThroughputUp to 96 samples per run
Extraction ChemistryMagnetic bead-based
Magnetic Bead TechnologyYes
UV DecontaminationYes
Power Requirements100-240 VAC, 50/60 Hz
Sample TypesBlood, plasma, serum, saliva, tissue, cells, plant material, forensic samples
Heating/CoolingIntegrated heating
ApplicationsGenomic DNA extraction, RNA extraction, Viral nucleic acid extraction
Operating Temperature15°C to 30°C
Humidity Range20-80% non-condensing
Sample Volume10 µL to 10 mL
Elution Volume50 µL to 500 µL

Summary

General Information

Changes from Previous Manual Version

Details changes made in this manual, marked with underlined text.

Trademarks

Lists registered trademarks of PerkinElmer and other companies.

General Information

Intended Purpose

Defines the chemagic 360-D as an IVD instrument for DNA and RNA extraction.

Table of Symbols

Explains various symbols used in the documentation and their meanings.

General Information

Principles of Operation

Explains the magnetic separation mechanism using metal rods and electromagnets.

Safety Information

Conventions

Explains the conventions used for warnings, cautions, and notes in the documentation.

Warnings and Precautions

Provides essential safety precautions for operating the chemagic 360-D instrument.

Safety Information

Electrical Safety Precautions

Details safety measures related to electrical connections and servicing of the instrument.

Biological Safety Precautions

Outlines precautions for handling potentially biohazardous materials and cleaning.

Computer Precautions

Advises on the correct use of the PC and software to prevent operational issues.

Electromagnetic Information and Precautions

Discusses EMC compliance and precautions related to electromagnetic fields.

Safety Information

Safety When Using the Equipment

Provides specific safety instructions for operating the instrument, including PPE and avoiding hazards.

Notice Regarding Serious Incidents

Instructions for reporting serious incidents related to the device in the EU and similar regulatory regions.

Installation and Calibration

Instrument Installation Requirements

States that installation and calibration must be done by trained and authorized personnel.

The chemagic Software

Software Overview

Introduces the software and its advanced features, requiring a license key.

Installing the chemagic Software

Details the software installation process, including required files and folders.

Starting the chemagic Software

Guides on how to launch the chemagic Software application.

Logging into the System

Explains the process of logging into the chemagic 360-D instrument's user interface.

The chemagic Software

Login and Rod Head Selection

Describes the login procedure and selecting the appropriate Rod Head type.

Main Program Window Overview

Introduces the main program window and its components after login.

The chemagic Software

Loading and Unloading Consumables

Details how to load and unload racks and consumables onto the instrument's tracking system.

The chemagic Software

Switching Off Procedure

Provides steps for safely powering down the instrument and associated PC.

Starting a Protocol with the chemagic 12 Rod Head

Initial Protocol Setup

Explains the initial steps for starting a protocol with the 12 Rod Head.

Running with Chemagic Dispenser

Details running protocols when the chemagic Dispenser is installed.

Running without Chemagic Dispenser

Guides on running protocols when the chemagic Dispenser is not installed.

Starting a Protocol with the chemagic 12 Rod Head

Entering Sample IDs (12 Rod Head)

Describes how to register sample IDs and their eluates for the isolation process.

Reading Sample IDs from File

Explains how to import sample IDs from a prepared text file.

Starting a Protocol with the chemagic 12 Rod Head

Entering Elution IDs

Details the process of entering or confirming elution IDs.

Starting a Protocol with the chemagic 12 Rod Head

Assigning IDs to Tube Racks

Guides on assigning individual IDs to buffer racks for better organization.

Starting a Protocol with the chemagic 12 Rod Head

Starting the Isolation Procedure

Provides final instructions and steps to begin the actual isolation run.

Starting a Protocol with the chemagic 24 Rod Head

Initial Protocol Setup (24 Rod Head)

Outlines the initial steps for starting a protocol with the 24 Rod Head.

Running with Chemagic Dispenser

Details running protocols with the chemagic Dispenser.

Running without Chemagic Dispenser

Guides running protocols without the chemagic Dispenser.

Starting a Protocol with the chemagic 24 Rod Head

Entering Sample IDs (24 Rod Head)

Describes how to register sample IDs for the 24 Rod Head.

Reading Sample IDs from File

Explains importing sample IDs from a file.

Starting a Protocol with the chemagic 24 Rod Head

Entering Elution IDs

Details entering or confirming elution IDs.

Starting a Protocol with the chemagic 24 Rod Head

Assigning IDs to Plates or Tube Racks

Guides on assigning IDs to plates/racks for buffer management.

Starting a Protocol with the chemagic 24 Rod Head

Starting the Isolation Procedure

Provides final steps before starting the isolation run.

Starting a Protocol with the chemagic 96 Rod Head

Initial Protocol Setup (96 Rod Head)

Outlines the initial steps for starting a protocol with the 96 Rod Head.

Running with Chemagic Dispenser

Details running protocols with the chemagic Dispenser.

Starting a Protocol with the chemagic 96 Rod Head

Entering Sample IDs (96 Rod Head)

Describes registering sample IDs for the 96 Rod Head.

Starting a Protocol with the chemagic 96 Rod Head

Entering Elution IDs

Details entering or confirming elution IDs.

Starting a Protocol with the chemagic 96 Rod Head

Assigning IDs to the Plates

Guides on assigning IDs to buffer plates.

Starting a Protocol with the chemagic 96 Rod Head

Starting the Isolation Procedure

Provides final instructions before starting the isolation run.

System Settings

System Settings Overview

Introduces the System Settings window for configuring the software and instrument.

System Settings

Edit User Settings

Explains how to manage user accounts, privileges, and passwords within the software.

System Settings

Display Log Files

Describes how to view and print log files generated during isolation runs.

Service and Maintenance

Cleaning the chemagic Dispenser

Details routine and intensive cleaning procedures for the chemagic Dispenser.

Displaying Software Version

Explains how to check the installed version of the chemagic Software.

Service and Maintenance

Changing chemagic Rod Heads

Instructions on how to remove and install different chemagic Rod Heads.

End-User Maintenance and Controls

Lists essential maintenance tasks and checks to be performed by the user.

Service and Maintenance

Checking and Priming Dispenser Manifolds

Describes checking and priming the dispenser manifolds for optimal performance.

Cleaning and Disinfection of Instrument

Provides instructions for comprehensive cleaning and disinfection of the instrument.

Service and Maintenance

Cleaning chemagic Rod Heads

Details how to clean the chemagic Rod Heads if contamination occurs.

Cleaning the Drop Cover

Instructions for cleaning the instrument's drop cover.

Moving the Instrument

Safety precautions and guidance for moving the instrument.

Specifications

Technical Specifications

Lists the physical dimensions, weight, power, and noise levels of the instrument.

Performance Specifications

Details the performance specifications of the buffer and washer liquid dispenser.

Environmental Conditions

Specifies the ambient temperature, humidity, and altitude requirements for operation.

Operator Requirements

Defines the qualifications and training required for instrument operators.

Error Messages

Errors During Software Startup

Lists error codes and messages that may occur during software startup.

Errors Reading/Saving Parameter Files

Lists errors related to reading and saving parameter files.

Error Messages

Errors Reading/Saving Protocol Files

Lists errors encountered while reading or saving protocol files.

Error Messages

Errors Editing Protocol Files

Lists errors that can occur when editing protocol files.

Error Messages

Errors Related to User Level

Lists errors and warnings related to user login and privilege levels.

Errors Related to Stripper Component

Lists error and warning messages specific to the stripper component.

Errors Related to Drop Cover

Lists error and warning messages related to the drop cover.

Error Messages

Errors During Protocol Execution

Lists errors occurring during the execution of a protocol file.

Errors Related to Instrument Covers

Lists errors related to the instrument covers not being closed properly.

Errors Related to Instrument Axes

Lists errors and warnings associated with the instrument's axes.

Error Messages

Communication Errors with Modules/Axes

Lists communication errors between the instrument and its modules/axes.

Error Messages

Internal Software Errors

Lists internal software errors that should not occur under normal conditions.

Troubleshooting

Instrument Not Switching On

Provides solutions for the instrument failing to power on.

Software Cannot Be Started

Offers steps to resolve issues when the chemagic Software fails to launch.

Communication Errors During Software Startup

Addresses communication errors that happen during software startup.

Software Freezes Due to Communication Errors

Provides solutions for communication errors causing the software to freeze.

Troubleshooting

X-Axis Status Not Green During Referencing

Solutions for when the X-axis status light doesn't turn green during referencing.

Rod Head Remains Low During Tip Take-up

Explains why the Rod Head might stay low during tip take-up and how to fix it.

Residual Magnetic Beads in Plates

Addresses residual magnetic beads in plates and when it's tolerable.

Warranty

Limited Instrument Warranty Summary

Summarizes the limited warranty terms for the instrument.

WEEE Instructions for PerkinElmer Products

Product Disposal Guidance

Provides guidance on the disposal of Waste Electrical and Electronic Equipment.

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