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Waters Xevo G2 QTof Service Manual

Waters Xevo G2 QTof
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Waters Xevo G2 QTof
Operators Overview and Maintenance Guide
Revision B
Copyright © Waters Corporation 20102011
All rights reserved

Table of Contents

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Waters Xevo G2 QTof Specifications

General IconGeneral
BrandWaters
ModelXevo G2 QTof
CategoryLaboratory Equipment
LanguageEnglish

Summary

Safety Considerations

Considerations Specific to the Xevo G2 QTof

Specific safety considerations for the Xevo G2 QTof instrument.

Solvent-Leakage Hazard

Hazards associated with solvent leaks and recommended precautions.

Flammable-Solvents Hazard

Hazards related to flammable solvents and safety measures.

1 Waters Xevo G2 QTof Overview

Waters Xevo G2 QTof

Overview of the Xevo G2 QTof mass spectrometry system.

LockSpray Source and Ionization Modes

Details on the LockSpray source and its ionization modes.

NanoLockSpray Source and Ionization Modes

Information on the NanoLockSpray source and its ionization modes.

IntelliStart Fluidics System

Explanation of the IntelliStart Fluidics system components and operation.

2 Preparing the Mass Spectrometer for Operation

Starting the Mass Spectrometer

Step-by-step guide for starting the mass spectrometer.

Preparing the IntelliStart Fluidics System

Procedures for preparing the IntelliStart Fluidics system.

Emergency Shutdown of the Mass Spectrometer

Procedure for safely shutting down the mass spectrometer in an emergency.

3 Configuring the LockSpray Source

Configuring the LockSpray Source

General steps to configure the LockSpray source for various ionization modes.

Configuring for ESI Mode

Detailed instructions for setting up the LockSpray source in ESI mode.

Configuring for APCI Mode

Detailed instructions for setting up the LockSpray source in APCI mode.

4 Configuring the NanoLockSpray Source

Overview of the NanoLockSpray Source

Description and illustration of the NanoLockSpray source.

Source Type Selection

How to select different sprayer types for the NanoLockSpray source.

Optional Glass Capillary Sprayer

Procedures for using the optional glass capillary sprayer.

5 Maintenance Procedures

Maintenance Schedule

Periodic maintenance schedules for optimal instrument performance.

Spare Parts

Information on recommended replacement parts and ordering.

Safety and Handling

General safety considerations and handling procedures during maintenance.

Replacing the ESI Probe Tip and Gasket

Steps to replace the ESI probe tip and gasket.

A Safety Advisories

Warning Symbols

Explanation of warning symbols and their associated risks.

Caution Symbol

Explanation of caution symbols and their implications.

Warnings That Apply to All Waters Instruments

General warnings applicable across all Waters instruments.

B External Connections

Mass Spectrometer External Wiring and Vacuum Connections

Diagram and explanation of rear panel connectors and vacuum ports.

Connecting the Varian Oil-Filled Roughing Pump

Step-by-step guide for connecting the Varian roughing pump.

Connecting the Edwards Oil-Free Roughing Pump

Step-by-step guide for connecting the Edwards oil-free roughing pump.

Connecting to the Nitrogen Gas Supply

Instructions for connecting the nitrogen gas supply.

C Materials of Construction and Compatible Solvents

Preventing Contamination

Information on preventing contamination in the instrument system.

Items Exposed to Solvent

Table listing instrument items and their materials exposed to solvents.

Solvents Used to Prepare Mobile Phases

Common solvents for mobile phases and their compatibility.

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