GFR
(See Figure 9-7.)
The following test is for the Glomerular Filtration Rate (GFR) test. This test uses Technetium-99m - DTPA
as the pharmaceutical. The GFR test is a renal function test of the kidneys. The procedure followed is
from the Journal of Nuclear Medicine Technology, Volume 14, Number 4, December 1986, entitled,
"Technical Aspects of a New Technique for Estimating Glomerular Filtration Rate Using Technetium-99m
- DTPA" by Kathrine R. Rowell, Frances N. Kontzen, Marian E. Stutzman, et al., V.A. Medical Center and
University of Alabama, Birmingham, Alabama. The program can have either one or two samples used in
the calculation.
Both the one and two sample methods follow the package inserts for Technetium DTPA for production of
the pharmaceutical. Look at the HELP SECTION for the Medical Spectrometer. There is a reproduction
of the procedure from the above mentioned article. The following instructions are for use of the Multi-
Channel Analyzer for counting the standard and sample(s) for getting your results.
GFR One Sample Method
(See Figure 9-8.)
1
At
the
<Patient
Definition>
window,
enter
a
new
patient
and
choose
the
appropriate
GFR
One
Sample or Two Sample test for an existing patient, or enter a new patient and choose the appropriate
GFR test.
2. Click on the Hematology Counting tab to bring up the counting screen. Verify that the patient and
ID# are correct.
3.
Click
on
<Preferences>
and
find
the
standard
to
dilution
ratio
and
quantity
used
to
count
for
both
the standard and the ultra filtrate. If you wish to enter any parameter, it should be done before
counting. Now click <OK> to close the GFR parameters window. Any changes will now be
implemented.
4. Clear away any radioactive sources from near the well counter. If you have not calibrated the well
counter today, do so now.
5. Place a test tube or vial similar to what you were using for the other samples to be tested into the
well counter. This will be used for background testing.
6. Click on <Background> and the system will proceed to count background. When done counting, it
will display the counts and the CPM.
7. Remove the background counting vial from the well counter and place the standard into the well
counter. Click on <Standard> to count the standard. When done counting, the system displays the
counts and the CPM.
8. Click on <Inject> to enter the time and date of injection. If you click on <Now>, it will bring the time
and date to the current date and time. You can then change this to whatever is appropriate. Click on
<OK> to set the date and time.
9. Click on <Time /Sample 1> and enter the time that the sample was drawn. Once you have entered
the time for the sample, click <OK> to record it. If you do not wish to save it, click <Cancel>.
NOTE: The GFR procedure calls out for a 3 hour sample withdrawal following the injection of the
pharmaceutical.
10. Place the sample into the well counter and click on <Sample>. The system will now count the
sample for the appropriate time and, when finished, display the counts and CPM.
CONTENTS
9-11 HEMATOLOGY
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