411829-L, Description and Specifications April 2012 Page 1-3
1
1.1.3 Programmed Functions
The Isolera system can be programmed to perform the following functions:
• Generate user-defined elution gradients
• Store and implement a large number of independent chromatographic methods
• Control and collect fractions based on light absorbance
• Collect fractions into a wide variety of collection racks and vessels
• Produce detailed, printable purification reports
1.1.4 User Documentation
The following documents are provided on the “Isolera User Documentation” CD (P/N 411831):
• “Isolera Installation and Safety”, P/N 411828
• “Isolera User Manual” (this publication), P/N 411829
• “Quick Guide for Isolera”, P/N 411830
• “Isolera Safety Translations”, P/N 412861
Online Help
To view context-sensitive help, press the Help button found in the right-hand panel. The following
buttons are available in the help window:
: View the safety requirements for the Isolera system. You must observe all these safety
requirements when installing and operating the Isolera system. Failure to install or use the system
in a manner specified by Biotage may result in personal injury and/or equipment damage.
: View instructions for tasks that can be performed in the present software mode (the Chemistry,
Data Administration, or System mode).
: View information on the tabs and buttons in the right-hand panel.
/ : Scroll down or up through the text (when a help window has more than one screenful of
information).
Back: Return to the last help topic that you viewed.
Close: Exit the help.
1.1.5 Accessories
Cartridges
The Isolera system is designed to operate with Biotage SNAP™, Biotage SNAP Ultra™ and Biotage
ZIP™ cartridges, which have easy-to-use Luer-lok™ connections. FLASH+
®
and ISOLUTE
®
cartridges can also be used but may require tube adapters and a separate ring stand.
All SNAP and SNAP Ultra disposable cartridge components are made from materials meeting USP
Class VI specifications, which minimize organic extractables providing cleaner fractions.
SNAP cartridges are available packed with silica (KP-Sil), high-performance silica (HP-Sil), C
18
(KP-
C18-HS), or NH (KP-NH) media. SNAP 750g and 1500g are available packed with silica (KP-Sil), C
18
(KP-C18-HS), or NH (KP-NH). Biotage ZIP cartridges are all packed with silica (KP-Sil).
SNAP Ultra cartridges deliver double the purification capacity of other flash cartridges by utilizing
Biotage HP-Sphere
™
, small particle, 25
μ
m spherical silica with a 40% increase in surface area. The
higher surface area provides twice the loading capacity of lower surface area silicas. This improved
load capacity means that a smaller SNAP Ultra cartridge can be used to replace a more expensive and
larger competitive cartridges.
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