FagronLab BASIC - Weighed Portion of the Formulation; The Mixing Process

FagronLab™ BASIC – User Manual | 22
FagronLab™ BASIC
The given mixing parameters are general procedures used to produce the routine standard formulations in pharmaceutical
preparation of compounds.
In the following, these standard formulations will be defined and the recommended procedure on weighing described. This will
produce a code of practice for orientation. This does not exclude other possible methods for optimisation.
For mixtures with high liquid content, ensure that the ointment foundation on the jar bottom is first carefully placed around the
sealing lip. This enhances the leak tightness of the jar.
The FagronLab™ BASIC is the result of continuous improvements. Featuring a guided lift arm, programmable mixing time and
mixing speed, the FagronLab™ BASIC is not just standard for the pharmacy.
The FagronLab™ BASIC is equipped with a quiet and constantly usable permanent motor and is the ointment mixing device for
individual and bulk compunding from 15 ml up to 500 ml.
To prepare compounds homogeneously, the FagronLab™ BASIC works in a rotation range from 300 up to 2400 rpm.
For every jar size dierent mixing parameters are already set in the FagronLab™ BASIC. These serve as recommended minimum
mixing time and minimum mixing speed. They have to be adjusted accordingly to each type of formulation.
Due to high rotation speed the levels 8 and 9 are not suitable for manufacturing in the jar sizes 300 ml and 500 ml, they are
disabled in the mixing time selection.
The mixing time can be set from 5 seconds to 99:30 minutes and the mixing motor in 10 levels from "0" to "9"
The exact rotation speed for each level are provided by the following table chart. The rotation speed is measured in the unit rpm.
After selecting jar size, mixing speed and time, move the lift arm into the lowest position.
The new FagronLab™ jar can be easily loaded into the lift arm due to the quick-lock coupling.
The mixing process
Level 0 1 2 3 4 5 6 7 8 9
Rotation speed (rpm) 300 600 800 1000 1200 1400 1650 1900 2150 2400
Tab: Value chart rotation speed
Weighed portion of the formulation
Generally, oily, greasy, aqueous and pulverized components can be weighed out into the jar all at the same time. However, it
is advantageous to consider certain general procedures to optimize the mixing results. Generally, know-how gained from the
traditional preparation of ointments is very helpful when using the mixing device. As already mentioned at the beginning of the
operating manual, true to the motto:
learning by doing