FagronLab™ BASIC – User Manual | 27
FagronLab™ BASIC
Gel
With the mixing parameter "Gel" gelling agents can be incorporated into fluids or semi-solid foundation.
As an example, the preparation of ultrasonic contact gel, hydroxypropyl cellulose 400. Also incorporation gelling agents like
bentonite or Aerosil into a semi-solid foundation.
To ensure a homogenous distribution we recommend applying disp. blades for jar sizes up to 200 ml and the standard mixing
blades for larger batches.
The fluid component will be weighed out first into the FagronLab™ jar. Soluble active substances can be administered directly into
the jar and dissolved. The gelling agent will be dispersed on top of the liquid component.
If the swelling agent will be incorporated into a semi-solid foundation, the gelling agent can be covered between two foundation
layers. This will obtain a faster dispersion of the gelling agent into the foundation.
Suppositories
With the mixing parameters "Suppositories", suppository compounds mixtures can be dispersed.
The suppository foundation can be warmed in a water bath directly in a transparent jar and afterwards stirred with the
FagronLab™ to the soft melting point. An applicator long aids in the precise filling of the suppository mould. For a batch
approximately 5 % to 10 % added allowance is recommended.
Step 1: moistening - Level 8 (2150 rpm)
Jar size 15 - 30 ml 50 - 100 ml 200 ml 300 - 500 ml
Time (min.) 0:30 0:30 0:30 1:00
Stirrer Disp. Blade Disp. Blade Disp. Blade SMB
Step 2: swelling phase - Level 1 (600 rpm)
Jar size 15 - 30 ml 50 - 100 ml 200 ml 300 - 500 ml
Time (min.) 8:30 9:30 10:00 10:00
Alternate the mixing steps at least twice or until a homogeneous gel structure is reached.
Tab: Mixing parameter Gel
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