Appendices P/N 53063-50, Manual Revision: B
APP-2
APPENDIX A: COMPLICATIONS AND CONTRAINDICATIONS
Complications of and contraindications to perioperative blood recovery
1
(Per 1997 AABB Guidelines for blood recovery and reinfusion in surgery and trauma pg 19-22)
Substance Effects Recommended Action
Pharmacologic Agents
A. Clotting Agents
1. Microfibrillar Products
Examples:
Avitene®, Helitene®, Oxycel®,
Gelfoam® Powder, Instat® MCH
May cause platelet
aggregation and clot
formation.
Reported to pass through a
microaggregate filter into
the blood stream causing
emboli.
Avoid aspiration when product is
being used. Resumption is an option
after copious irrigation with 0.9%
sodium chloride solution to an
alternate suction source.
2. Sponge/Fabric Materials
Examples:
Surgicel™, Surgicel™ Nu-Knit®,
Gelfoam® Sponge, Helistat®,
Instat™, Hemopad®, Super Stat®,
HemoFoam®
Activates clotting sequence
by acting as a contact
agent.
May clot off system.
Avoid aspiration in area where
product is being used. Resumption
is an option after copious irrigation
with 0.9% sodium chloride solution
to an alternate suction source.
3. Topical Liquids
Examples:
Thrombin-JMI™, Thrombostat®,
Thrombogen®
Creates a fibrin clot by
direct action on fibrinogen.
May clot off system.
Avoid aspiration in area where
product is being used. Resumption
is an option after copious irrigation
with 0.9% sodium chloride solution
to an alternate suction source.
B. Irrigating Solutions
1. Alcohol Causes red cell lysis. Avoid aspiration in area where
product is being used. Resumption
is an option after copious irrigation
with 0.9% sodium chloride solution
to an alternate suction source.
2. Antibiotics
Examples: Bacitracin, Neomycin,
Polymyxin
Can result in renal and
neuro toxicity if blood is
not washed.
Increase amount of wash volume by
500 ml.
3. Betadine Causes red cell lysis. Avoid aspiration in area where
product is being used. Resumption
is an option after copious irrigation
with 0.9% sodium chloride solution
to an alternate suction source.
To Next Page
Loading...
