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Thermo Scientific TSQ 9000 User Manual

Thermo Scientific TSQ 9000
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TSQ 9000
Mass Spectrometer
Hardware Manual
1R120618-0003 Revision C December 2018

Table of Contents

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Thermo Scientific TSQ 9000 Specifications

General IconGeneral
Mass Spectrometer TypeTriple Quadrupole
Operating Temperature15-30 °C (59-86 °F)
Ionization SourceElectrospray Ionization (ESI), Atmospheric Pressure Chemical Ionization (APCI)
ResolutionUp to 0.7 Da
Data AcquisitionSelected Reaction Monitoring (SRM), Full Scan, Product Ion Scan, Precursor Ion Scan, Neutral Loss Scan
SoftwareThermo Scientific™ Xcalibur™
Polarity SwitchingFast polarity switching
Operating Humidity20-80% (non-condensing)
Power Requirements100-240 V, 50/60 Hz
WeightApprox. 220 lbs (100 kg)

Summary

Preface

About Your System

Provides an overview of the TSQ 9000 system and its capabilities in GC/MS analysis.

Related Documentation

Lists other manuals and help resources available for the TSQ 9000 system.

System Requirements

Details the minimum hardware and software specifications for the TSQ 9000 data system.

Safety and Special Notices

Highlights important safety information, including symbols and signal words used in the manual.

Hydrogen Safety Precautions

Provides detailed safety guidelines and recommendations for using hydrogen as a carrier gas.

Hazardous Substances Precautions

Outlines precautions for handling hazardous chemicals and biological compounds.

Venting Toxic Gases

Advises on venting toxic gases from the system to a fume hood.

Contacting Us

Provides information on how to contact Thermo Fisher Scientific for support.

Performing Routine Maintenance

Maintenance Supplies and Tools

Lists necessary supplies and tools for performing routine maintenance on the TSQ 9000 instrument.

Configuring the TSQ 9000 System

Step-by-step guide for setting up and configuring the TSQ 9000 instrument after installation or reconfiguration.

Powering On the TSQ 9000 System

Instructions for correctly powering on the TSQ 9000 mass spectrometer and checking system status lights.

Powering Off the TSQ 9000 System

Procedures for safely shutting down and powering off the TSQ 9000 mass spectrometer.

Replacing a Column

Detailed instructions for replacing the GC column, depending on system configuration.

Maintaining the Foreline Pump

Guidance on routine maintenance of the foreline (roughing) pump, including oil changes.

Removing the Ion Source Cartridge for Cleaning

Step-by-step instructions for removing the ion source cartridge for cleaning to maintain performance.

Maintaining the Calibration Gas Module

Information on maintaining the calibration gas module, primarily refilling the calibrant reservoir.

Replacing a Dual Filament

Procedures for replacing the dual filament in the ion source when it fails or wears out.

Replacing the Electron Multiplier

Steps for replacing the electron multiplier, a component related to detector sensitivity.

Cleaning Durable Components

Instructions for cleaning specific durable components within the vacuum manifold of the TSQ 9000.

Cleaning Delicate Components

Guidelines for cleaning delicate components within the vacuum manifold, emphasizing careful handling.

Cleaning the Filters

Procedures for cleaning or replacing the various filters and fan filters on the TSQ 9000 instrument.

Troubleshooting

Using Diagnostics

Explains how to run software diagnostics to detect and resolve instrument problems.

Investigating Communication Issues

Addresses problems related to the instrument's communication with the computer and software.

Investigating Contamination Issues

Discusses common causes of chemical noise and contamination in the system and how to minimize them.

Investigating Filament and Lens Control Issues

Covers troubleshooting related to the filament and lens control systems of the mass spectrometer.

Investigating Temperature Issues

Provides guidance on diagnosing and resolving problems with heated zones like the ion source and transfer line.

Investigating Vacuum Issues

Details troubleshooting steps for issues related to the instrument's vacuum system and pumps.

Investigating Power Supply Issues

Addresses problems related to the instrument's power supply, including failure to power on.

Investigating RF/DC Issues

Covers troubleshooting for problems concerning the RF/DC system, such as incorrect RF dip.

Investigating Sensitivity Issues

Explains how to diagnose and resolve issues related to instrument sensitivity and response.

Investigating Stability Issues

Addresses problems causing inconsistent precision and irreproducible results, affecting instrument stability.

Investigating Tuning Issues

Guides users on troubleshooting automatic tune failures and identifying the root cause.

Contacting Technical Support

Provides instructions on how to contact technical support for further assistance with troubleshooting.

Advanced Troubleshooting

Replacing Components of the Analyzer

Details the process of removing and replacing components of the analyzer, such as ion source and quadrupoles.

Replacing Components of the Ion Source

Provides instructions for replacing individual components of the ion source assembly.

Replacing Components of the Vacuum Interlock

Explains how to replace damaged components of the vacuum interlock system.

Replacing Components of the Manifold

Covers the replacement procedures for various components of the instrument's manifold.

Replacing Components of the Electron Multiplier

Guides users on replacing the electron multiplier, a component that requires frequent replacement.

Reinstalling the TSQ 9000 System Software

Describes the process of updating instrument firmware and upgrading software on the computer.

Replacing the Covers of the TSQ 9000 Instrument

Instructions for replacing damaged outer covers of the TSQ 9000 instrument.

Replacing Components of the Front Door

Details how to replace components of the instrument's front door, such as hinges and latches.

Replacing the Boards in the TSQ 9000 Instrument

Procedures for replacing various electronic boards within the TSQ 9000 instrument.

Replacing the Power Supplies

Instructions for replacing the instrument's power supply modules.

Replacing the Calibration Gas Components

Guidance on replacing components related to the calibration gas system.

Replacing the Collision Gas Components

Instructions for replacing components of the collision gas system.

Replacing Fans and Filters

Procedures for replacing or cleaning cooling fans and filters to maintain instrument temperature.

Replacing the Turbomolecular Pump

Step-by-step guide for installing or replacing the turbomolecular pump.

Convectron Gauge and Foreline Adapter with Hose

Instructions for replacing the convectron gauge and foreline adapter assembly.

Upgrade Equipment

Advanced EI Ion Source

Instructions for installing the Advanced EI ion source as an upgrade.

Dust Filter

Information on installing the optional dust filter to protect internal components.

CI Reagent Gas Flow Module

Steps for installing a new CI reagent gas flow module to control reagent gas flow.

CI Ion Volume

Guidance on replacing the EI ion volume with a CI ion volume.

EI/CI Ion Volume

Information on installing a combined EI/CI ion volume for dual-mode operation.

Ion Gauge and Tube Shield

Instructions for installing an ion gauge and its associated tube shield.

Probe Controller

Details on installing a probe controller for direct sample probes used in the ion source.

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