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General| Mass Analyzer | Triple quadrupole |
|---|---|
| Polarity Switching | Yes |
| Ion Source Options | APCI |
| Data Acquisition/Scan Modes | Full Scan, Product Ion Scan, Precursor Ion Scan, Neutral Loss Scan |
| Software | Thermo Scientific Xcalibur |
| Power Requirements | 50/60 Hz |
Describes the typical workflow and components of an LC/MS analysis.
Overview of different MS and MS/MS scan types like Full Scan, SIM, SRM for data acquisition.
Explains one-stage mass analysis using Q1 or Q3 as the mass analyzer for full spectra.
Monitors specific ions for trace analysis and rapid screening of target compounds.
Two-stage analysis measuring fragment ions from a selected precursor ion.
Detects precursor ions that fragment to produce a specific product ion.
Detects precursor ions that lose a specific neutral mass during fragmentation.
Information on forepumps and the internal turbomolecular pump for vacuum generation.
Discusses API sources (EASY-Max NG, Ion Max NG) and ionization techniques.
Describes the components under vacuum within the API source interface.
Details the components that focus and transmit ions from source to analyzer.
Explains quadrupole rod assemblies, RF/DC fields, and the mass analysis process.
Describes the high-sensitivity ion detection system and its pulse counting/analog modes.
Procedure for immediate power-off of the MS using the main power switch.
Steps for a full system shutdown for extended periods or maintenance.
Daily checks for system mode, vacuum levels, and gas supplies before analysis.
Daily maintenance procedures after analysis completion.
Lists recommended frequencies for various MS maintenance procedures.
Procedures for cleaning and servicing the API source interface components.
How to execute diagnostic tests to check electronic circuits and identify issues.
Information on fuses and the need for service engineer for PCB/power supply replacement.
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