Thermo Scientific TSQ Endura and TSQ Quantiva Hardware Manual 55
Daily Operation
To ensure the proper operation of the TSQ Endura or TSQ Quantiva system, Thermo Fisher
Scientific recommends that you perform daily preventive maintenance. This chapter specifies
the items to check before operating the system and the cleaning procedures to perform after
completing the analyses.
Clean the ion sweep cone, the spray cone, and the ion transfer tube on a regular basis to
prevent corrosion and to maintain optimum performance of the API source; see Cleaning the
Ion Sweep Cone, Spray Cone, and Ion Transfer Tube. If you use a mobile phase that contains
a nonvolatile buffer or inject high concentrations of sample, you might need to clean these
parts more often. It is not necessary to vent the system to flush the ion sweep cone and ion
transfer tube.
Before Operating the Mass Spectrometer
Follow these preventive maintenance procedures every day before beginning the first analysis:
• Checking the System Mode
• Checking the Vacuum Pressure Levels
• Checking the Gas Supplies
• Checking the oil level of the forepumps (See Maintaining the Forepumps.)
Note You do not need to calibrate and tune the mass spectrometer as part of your daily
routine. Generally, you must calibrate the mass spectrometer every one to three months of
operation for optimum performance over the entire mass range of the mass detector.
For information about calibration, refer to the TSQ Endura and TSQ Quantiva Getting
Started Guide.
Contents
• Before Operating the Mass Spectrometer
• After Operating the Mass Spectrometer