Agilent Triple Quadrupole MS and Sensitivity 3
Front-end ion optics
Agilent 6400 Series Triple Quad LC/MS Concepts Guide 55
Front-end ion optics
The key components are shown in Figure 25. The triple
quadrupole leverages the same front end optics as the single
quadrupole mass spectrometer. An additional improvement was
made for the 6460A in the vacuum region right behind the
skimmer. This improvement allowed for increased pumping
throughput in this region which leads to a modest increase in
signal.
For the Agilent 6490A, the skimmer is replaced by the Dual Ion
Funnel technology which is described in “Innovative
Enhancements in the 6490 Triple Quadrupole" on page 23.
The 6490 changed the Dielectric capillary to a short hexabore
capillary. It has 6 capillary inlets, and it is half as long. It
samples up to 10 times more ion rich gas from the source. It
captures the majority of the gas from the source region.
Dielectric capillary
Small diameter octopole ion guide
(skimmer)
High frequency RF octopole
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