9300015500 Rev. C 12 of 14 Pre-installation Instructions
The following illustrate how critical LC/MS grade solvents are for optimum performance. The MS
is sensitive enough to detect impurities in HPLC solvents, which can cause a very noisy
baseline.
Figure 4 Signal-to-Noise Ratio with HPLC Grade Solvents
Figure 5 Signal-to-Noise Ratio with LC/MS Grade solvents
Additional tubing is required to complete installation. Most of this tubing is included in the
accessory kits of the LC modules. Additional tubing (PEEK™ or stainless steel) may be required
for installation of special valves or modules. For most analytical HPLC systems, use 1/16 in. OD
tubing with an ID of 0.005 in. To prevent peak broadening use at least 0.005 in ID downstream
of the sample injector and autosampler. Keep tubing as short as possible to prevent peak
broadening and to minimize run time.
;
Check the checklist box: Materials and solvents of specified grade are on site.
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