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VF, DHT, AES Series Manual |
Refrigerated Air Dryer User Manual
71
C.2 R-404a Refrigerant
June 10, 2015 (rev. 1)
SAFETY DATA SHEET R-404A
6
HAZARDOUS DECOMPOSITION PRODUCTS:
Halogens, halogen acids and possibly carbonyl halides. These materials are toxic and irritating.
HAZARDOUS POLYMERIZATION:
Will not occur.
11. TOXICOLOGICAL INFORMATION
IMMEDIATE (ACUTE) EFFECTS:
HFC-134a: LC
50 : 4 hr. (rat) - > 500,000 ppm / Cardiac Sensitization threshold (dog) > 80,000 ppm
HFC-143a: LC
50 : 4 hr. (rat) - > 540,000 ppm / Cardiac Sensitization threshold (dog) > 250,000 ppm
HFC-125: LC
50: 4 hr. (rat) - > 800,000 ppm / Cardiac Sensitization threshold (dog) 75,000 ppm
DELAYED (SUBCHRONIC AND CHRONIC) EFFECTS:
HFC-134a: Teratogenic NOEL(rate and rabbit) – 40,000 ppm
Subchronic inhalation NOEL (rat) - 50,000 ppm / Chronic NOEL – 10,000 ppm
HFC-125: Teratogenic NOEL (rat and rabbit) – 50,000 ppm
Subchronic inhalation (rat) NOEL - >50,000 ppm / Chronic NOEL – 10,000 ppm
HFC-143a: Teratogenic NOEL (rat and rabbit) – 50,000 ppm
Subchronic inhalation NOEL (rat) - >
50,000 ppm
OTHER DATA:
HFC-125, HFC-134a: Not active in four genetic studies
HFC-143a: Not active in two genetic studies
Toxicity to reproduction: Did not show mutagenic or teratogenic effects in animal experiments
12. ECOLOGICAL INFORMATION
Aquatic Toxicity:
HFC 143a 96-hour LC50. Rainbow trout: >40mg/L
HFC 134a 48-hour EC50, Daphnia magna: 980 mg/L
96-hour LC50. Rainbow trout: >450mg/L
Degradability (BOD): R-404A is a gas at room temperature; therefore, it is unlikely to remain in water.
Octanol Water Partition Coefficient: Unknown for mixture
13. DISPOSAL CONSIDERATIONS
RCRA - Not a hazardous waste.
OTHER DISPOSAL CONSIDERATIONS:
Disposal must comply with federal, state, and local disposal or discharge laws. R-404A is subject to U.S.
Environmental Protection Agency Clean Air Act Regulations Section 608 in 40 CFR Part 82 regarding refrigerant
recycling.

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