SPECIFICATIONS
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109
Chapter 9
Whole-Cell Capacitance
β = 1
:
0.3 - 100 pF
β = 0.1
:
3 - 1000 pF
Series Resistance
0 - 100 MΩ
These controls are used to charge membrane capacitance in whole-cell voltage clamp. For
PATCH mode, whole-cell capacitance is not operative. In I-CLAMP modes only the
SERIES RESISTANCE control is operative. The whole-cell capacitance control places an
analog voltage proportional to setting on CELL CAPACITANCE TELEGRAPH OUTPUT.
The range of values for the SERIES RESISTANCE compensation control is 0 - 100 MΩ .
Series Resistance Compensation
% Prediction
OFF, 0-100 %. Acts with WHOLE-CELL PARAMETERS to speed up charging of the
membrane. Maximum achievable % PREDICTION is limited by magnitude of voltage step
(see Figure 4).
% Correction
OFF, 0-100%. Acts with SERIES RESISTANCE setting to reduce series resistance errors
and speed up response to ionic currents.
Lag
1-100 µs. Cuts high-frequency response of series-resistance correction circuit to enable a
higher CORRECTION setting.
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