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Endress+Hauser Liquisys M CLM253 - Limit Values for Pharmaceutical Water

Endress+Hauser Liquisys M CLM253
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Liquisys M CLM223/253 Commissioning
Endress+Hauser 59
A
B
C
t
0
t
1
t
2
t
3
t
4
t
5
0
0
0
1
1
1
A0025216
 35 Sequence of a cleaning cycle
A Hold function
B Water valve is triggered
C Cleaning valve is triggered
0 Contact off
1 Contact on
t0 Normal operation
t1 cleaning start
t2-t1Pre-rinse time
t3-t2Cleaning time
t4-t3Post rinse time
t5-t4Hold dwell period
Limit values for pharmaceutical water according to United States Pharmacopoeia
(USP) and European Pharmacopoeia (EP) (only for conductive sensors)
In the case of conductive sensors, the transmitter has functions for monitoring "Water for
Injection" (WFI), "Highly Purified Water" (HPW) and "Purified Water" (PW) according to the
United States Pharmacopoeia (USP) Part 645 and European Pharmacopoeia (EP)
standards.
USP function: The temperature-dependent limit values in the following table apply for
"Water for Injection" (WFI) according to USP and EP and for "Highly Purified Water" (HPW)
according to EP. The table is programmed into the transmitter.
Temperature [°C] Conductivity [µS/cm] Temperature [°C] Conductivity [µS/cm]
0 0.6 55 2.1
5 0.8 60 2.2
10 0.9 65 2.4
15 1.0 70 2.5
20 1.1 75 2.7
25 1.3 80 2.7
30 1.4 85 2.7
35 1.5 90 2.7
40 1.7 95 2.9
45 1.8 100 3.1
50 1.9

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